Interactor 1: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Interactor 2: CHD5 (Q8TDI0)
Chromodomain-helicase-DNA-binding protein 5 (CHD-5) (EC 3.6.4.12) (ATP-dependent helicase CHD5)
Gene: CHD5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 25247294, 32744500, 21555454
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo, Chromo~PHD, Chromo~SNF2-rel_dom, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom, PHD~PHD, SNF2-rel_dom~SNF2-rel_dom
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity
and 9 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1912
Hs

1 1954
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+ Dm
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+ Sp
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Last updated: 15 Jul 2024