Interactor 1: BAX (Q07813)
Apoptosis regulator BAX
Gene: BAX
Interactor 2: ERN1 (Q9EQY0)
Serine/threonine-protein kinase/endoribonuclease IRE1 (Endoplasmic reticulum-to-nucleus signaling 1) (Inositol-requiring protein 1) (Ire1-alpha) (IRE1a) [Includes: Serine/threonine-protein kinase (EC 2.7.11.1); Endoribonuclease (EC 3.1.26.-)]
Gene: ERN1
Species: Mus musculus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16645094 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0005789 - endoplasmic reticulum membrane GO:0030544 - Hsp70 protein binding GO:0042803 - protein homodimerization activity GO:0070059 - intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
