Protein: DOCK3
Dedicator of cytokinesis protein 3 (Modifier of cell adhesion) (Presenilin-binding protein) (PBP)

Gene: DOCK3
Organism: Homo sapiens
Interactions: 58
UniProt ID: Q8IZD9

Gene Ontology (top 5):
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1224220

ELMO1
Engulfment and cell motility protein 1

6

20

Small-scale

0.942

High

1224227

ELMO2
Engulfment and cell motility protein 2

3

20

High-throughput

0.839

High

1224225

ELMO3
Engulfment and cell motility protein 3

2

20

High-throughput

0.811

High

1224218

DOCK4
Dedicator of cytokinesis protein 4

1

12

High-throughput

0.691

High

1054780

CASL
Enhancer of filamentation 1

1

7

Small-scale

0.665

High

925425

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.647

High

337501

ABL1
Tyrosine-protein kinase ABL1

1

7

High-throughput

0.618

High

412257

FYN
Tyrosine-protein kinase Fyn

1

7

High-throughput

0.618

High

523056

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

High-throughput

0.618

High

557736

NCK1
SH2/SH3 adapter protein NCK1

1

15

High-throughput

0.618

High

655417

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

6

High-throughput

0.618

High

802655

CRK
Adapter molecule crk

1

20

High-throughput

0.618

High

924695

GRB2
Growth factor receptor-bound protein 2

1

17

High-throughput

0.618

High

1022684

RHG05
Rho GTPase-activating protein 5

2

5

High-throughput

0.594

High

164959

SC16A
Protein transport protein Sec16A

2

6

High-throughput

0.571

High

173738

SURF4
Surfeit locus protein 4

2

1

High-throughput

0.571

High

657384

ABCD3
ATP-binding cassette sub-family D member 3

2

2

High-throughput

0.571

High

878200

SEC13
Protein SEC13 homolog

2

4

High-throughput

0.571

High

1049839

UBP2L
Ubiquitin-associated protein 2-like

2

10

High-throughput

0.571

High

1080718

ZYX
Zyxin

2

1

High-throughput

0.571

High

1224221

GCN1
Stalled ribosome sensor GCN1

2

4

High-throughput

0.571

High

1224230

TRAF4
TNF receptor-associated factor 4

2

2

High-throughput

0.571

High

829937

HXA1
Homeobox protein Hox-A1

2

5

High-throughput

0.553

High

1224233

PKHF2
Pleckstrin homology domain-containing family F member 2

2

2

High-throughput

0.553

High

531901

PDIA4
Protein disulfide-isomerase A4

2

2

High-throughput

0.549

High

198665

PSMD3
26S proteasome non-ATPase regulatory subunit 3

2

0

High-throughput

0.547

High

488287

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

0

High-throughput

0.547

High

1224222

AKAP1
A-kinase anchor protein 1, mitochondrial

2

0

High-throughput

0.547

High

1224238

HACD3
Very-long-chain

2

0

High-throughput

0.547

High

563633

ZNF24
Zinc finger protein 24

2

1

High-throughput

0.521

High

1224232

ZN768
Zinc finger protein 768

2

2

High-throughput

0.521

High

1224239

DHCR7
7-dehydrocholesterol reductase

2

2

High-throughput

0.521

High

1224219

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

1224235

DDX21
Nucleolar RNA helicase 2

1

3

High-throughput

0.515

High

1224224

AIDA
Axin interactor, dorsalization-associated protein

1

0

High-throughput

0.513

High

1224229

TREX2
Three prime repair exonuclease 2

1

0

High-throughput

0.513

High

1224240

TBC24
TBC1 domain family member 24

1

0

High-throughput

0.513

High

942787

SRPK2
SRSF protein kinase 2

1

7

High-throughput

0.501

High

377478

GCR
Glucocorticoid receptor

1

12

Small-scale

0.481

High

162973

XPO1
Exportin-1

1

4

High-throughput

0.479

High

198929

RFOX2
RNA binding protein fox-1 homolog 2

1

5

High-throughput

0.479

High

1047884

CIRBP
Cold-inducible RNA-binding protein

1

2

High-throughput

0.479

High

1201987

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

2

High-throughput

0.479

High

1224236

SIR5
NAD-dependent protein deacylase sirtuin-5, mitochondrial

1

4

High-throughput

0.479

High

1224241

MAGD2
Melanoma-associated antigen D2

1

3

High-throughput

0.479

High

1086214

H31T
Histone H3.1t

1

7

High-throughput

0.470

High

678648

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.458

High

1224226

P5CR2
Pyrroline-5-carboxylate reductase 2

1

2

High-throughput

0.437

High

1224228

YMEL1
ATP-dependent zinc metalloprotease YME1L1

1

2

High-throughput

0.437

High

1224237

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

1

High-throughput

0.437

High

991817

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

3

Small-scale

0.408

High

879695

ATPK
ATP synthase subunit f, mitochondrial

2

0

High-throughput

0.298

High

1114309

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

2

0

High-throughput

0.298

High

1224223

CCD47
PAT complex subunit CCDC47

2

0

High-throughput

0.298

High

1224231

REPI1
Replication initiator 1

2

0

High-throughput

0.298

High

1224234

RM47
Large ribosomal subunit protein uL29m

2

0

High-throughput

0.298

High

1224217

H6ST3
Heparan-sulfate 6-O-sulfotransferase 3

1

0

High-throughput

0.279

Low

1224242

HS3S4
Heparan sulfate glucosamine 3-O-sulfotransferase 4

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024