HitPredict

Interactor 1: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31300519
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0044877 - protein-containing complex binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2115 Hs			1 581
+	Hs
		1047932 NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00		KCC1A_HUMAN (211-573): 1.25e-100: 311: 18.28
+	Hs
		724998 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		725236 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		1068650 PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37		PINK1_HUMAN (1-581): 7.17e-159: 468: 100.00
+	Hs
		681696 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		AKT1_HUMAN (115-573): 2.58e-118: 360: 12.89
+	Hs
		568567 MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568568 MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		518859 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		KPCZ_HUMAN (54-568): 6.17e-114: 353: 13.97
+	Hs
		518814 TPR_HUMAN (2-620): 2.42e-18: 94.7: 12.04		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89
+	Hs
		568720 CNTRL_HUMAN (3-811): 1.27e-16: 89.3: 11.29		KAPCA_HUMAN (173-567): 1.06e-110: 336: 13.89