Interactor 1: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7
Interactor 2: FBXW8 (Q8N3Y1)
F-box/WD repeat-containing protein 8 (F-box and WD-40 domain-containing protein 8) (F-box only protein 29)
Gene: FBXW8
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.979 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18498745, 31343991, 12481031, 34478796, 16142236, 17205132, 21946088, 21572988, 17332328, 23029530, 17998335, 23045529, 12904573 |
| Identification Methods | affinity chromatography technology, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~F-box-like |
| Common GO terms | GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0007030 - Golgi organization GO:0016567 - protein ubiquitination GO:0031467 - Cul7-RING ubiquitin ligase complex and 2 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Rn |   |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
