HitPredict

Interactor 1: CUL7 (Q14999)
Cullin-7 (CUL-7)
Gene: CUL7

Interactor 2: CCDC8 (Q9H0W5)
Coiled-coil domain-containing protein 8
Gene: CCDC8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	24711643, 25752541, 31343991
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000226 - microtubule cytoskeleton organization GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol GO:0007088 - regulation of mitotic nuclear division and 1 others more... GO:1990393 - 3M complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1698 Hs			1 538
+	Hs
		1061676 CUL7_HUMAN (1-1698): 0: 2861: 100.00		PNMA2_HUMAN (1-97): 9.69e-36: 138: 36.08
+	Hs
		1219371 CUL9_HUMAN (1-782): 0: 910: 45.71		CCDC8_HUMAN (1-538): 0: 665: 100.00
+	Hs
		320006 HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55		CCDC8_HUMAN (1-538): 0: 665: 100.00
+	Hs
		320059 HERC2_HUMAN (838-982): 1.36e-38: 161: 36.55		PNMA2_HUMAN (1-97): 9.69e-36: 138: 36.08