HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: PRC2B (Q5JSZ5)
Protein PRRC2B (HLA-B-associated transcript 2-like 1) (Proline-rich coiled-coil protein 2B)
Gene: PRRC2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 494 Hs			1 2229
+	Hs
		550316 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		PRC2B_HUMAN (1-2229): 0: 638: 100.00
+	Hs
		550367 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		KMT2C_HUMAN (86-2064): 1.77e-62: 240: 9.54
+	Hs
		1060981 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		MDC1_HUMAN (92-1014): 1.36e-41: 171: 10.30
+	Hs
		1061211 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1098963 SRSF9_HUMAN (3-216): 2.37e-52: 178: 36.53		MDC1_HUMAN (92-1014): 1.36e-41: 171: 10.30
+	Hs
		1099075 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		MDC1_HUMAN (92-1014): 1.36e-41: 171: 10.30
+	Hs
		1099605 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1062155 SRSF4_HUMAN (1-468): 4.58e-48: 174: 100.00		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1099309 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1099491 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		MINT_HUMAN (8-1813): 2.71e-32: 140: 6.95
+	Hs
		1061227 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67
+	Hs
		550527 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		SRRM2_HUMAN (15-2006): 1.8e-37: 157: 9.78
+	Hs
		1099486 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		CIC_HUMAN (18-1410): 3.93e-17: 90.9: 8.32
+	Hs
		1030690 PABP3_HUMAN (3-189): 9.41e-29: 122: 19.19		ANK2_HUMAN (407-2171): 1.72e-28: 128: 9.19
+	Hs
		550381 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		TITIN_HUMAN (59-1179): 4.76e-22: 107: 7.87
+	Hs
		550544 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		PRC2C_HUMAN (28-2045): 2.08e-20: 101: 7.67
+	Hs
		550171 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67
+	Hs
		1102036 PABP4_HUMAN (101-185): 3.05e-11: 67.7: 20.00		TITIN_HUMAN (59-1179): 4.76e-22: 107: 7.87
+	Hs
		875649 PABP4_HUMAN (101-185): 3.05e-11: 67.7: 20.00		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67
+	Hs
		875630 TIAR_HUMAN (96-188): 1.12e-09: 61.9: 16.67		PRC2A_HUMAN (61-1403): 3.91e-16: 87.4: 8.67