HitPredict

Interactor 1: SRSF4 (Q08170)
Serine/arginine-rich splicing factor 4 (Pre-mRNA-splicing factor SRP75) (SRP001LB) (Splicing factor, arginine/serine-rich 4)
Gene: SRSF4

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 9531537
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000375 - RNA splicing, via transesterification reactions GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 2 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 494 Hs			1 904
+	Hs
		1061051 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		SRRM1_HUMAN (1-904): 1.53e-74: 264: 100.00
+	Hs
		1099429 SRSF6_HUMAN (1-180): 4.54e-52: 181: 78.50		SRRM1_HUMAN (1-904): 1.53e-74: 264: 100.00
+	Hs
		1099155 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		SRRM1_HUMAN (1-904): 1.53e-74: 264: 100.00
+	At
		1318541 SR30_ARATH (4-253): 1.46e-54: 185: 36.33		Q8L7W3_ARATH (1-882): 3.57e-50: 193: 23.53
+	Sp
		1008987 SRP2_SCHPO (3-345): 2.26e-43: 158: 31.55		YJQ5_SCHPO (3-290): 6.94e-54: 191: 28.24
+	Hs
		1060981 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Hs
		139701 SRSF1_HUMAN (3-166): 2.37e-57: 192: 41.42		CAC1A_HUMAN (94-637): 2.18e-09: 63.6: 14.46
+	Hs
		1098963 SRSF9_HUMAN (3-216): 2.37e-52: 178: 36.53		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Hs
		1099075 SRSF5_HUMAN (3-256): 1.26e-49: 172: 53.85		MDC1_HUMAN (197-904): 2.34e-09: 63.8: 8.82
+	Hs
		550367 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		KMT2C_HUMAN (286-894): 4.08e-09: 63.1: 9.67
+	Hs
		1030690 PABP3_HUMAN (3-189): 9.41e-29: 122: 19.19		ANK2_HUMAN (110-849): 7.8e-11: 68.6: 14.10
+	Hs
		550381 PABP1_HUMAN (1-189): 3.74e-31: 128: 19.50		TITIN_HUMAN (121-903): 8.89e-09: 61.9: 11.69
+	Hs
		1186302 RBM4B_HUMAN (3-104): 4.7e-11: 66.1: 23.08		MA7D1_HUMAN (116-903): 8.94e-28: 122: 10.90
+	Ce
		145091 UNC89_CAEEL (154-403): 1.78e-22: 103: 19.70		UNC22_CAEEL (254-904): 3.3e-14: 79.8: 15.42
+	Hs
		1102036 PABP4_HUMAN (101-185): 3.05e-11: 67.7: 20.00		TITIN_HUMAN (121-903): 8.89e-09: 61.9: 11.69