HitPredict

Interactor 1: SART3 (Q15020)
Squamous cell carcinoma antigen recognized by T-cells 3 (SART-3) (Tat-interacting protein of 110 kDa) (Tip110) (p110 nuclear RNA-binding protein)
Gene: SART3

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	1.00	0.919

Property	Details
Experiments	28514442, 26725010, 29845934, 33961781, 18281698
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0017070 - U6 snRNA binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 582
+	Hs
		403228 SART3_HUMAN (1-963): 0: 638: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		1063298 SART3_HUMAN (1-963): 0: 638: 100.00		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		1063232 SART3_HUMAN (1-963): 0: 638: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		300169 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116304 PAP1L_HUMAN (610-903): 6.47e-46: 177: 13.90		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		300187 PRP6_HUMAN (20-640): 4.55e-83: 290: 13.10		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		1174813 PRP39_HUMAN (55-644): 1.25e-71: 252: 13.27		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		403090 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		641756 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		516364 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		1022282 CSTF3_HUMAN (88-585): 1.96e-82: 283: 16.18		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		641955 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		403212 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Mm
		641996 U2AF2_MOUSE (620-894): 2.18e-65: 229: 23.03		TIA1_MOUSE (120-325): 5.06e-24: 106: 13.94
+	Sc
		376663 NSR1_YEAST (693-880): 1.88e-48: 180: 28.50		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		474021 PABP4_HUMAN (605-903): 3.97e-45: 175: 17.67		PAB4L_HUMAN (1-203): 9.24e-35: 136: 11.85
+	Hs
		641827 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23
+	Hs
		1119141 PAP1L_HUMAN (610-903): 6.47e-46: 177: 13.90		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		641802 U2AF2_HUMAN (620-894): 8.59e-67: 233: 23.36		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50
+	Hs
		1077450 DAZP1_HUMAN (697-939): 3.76e-61: 215: 23.41		ELAV1_HUMAN (92-211): 7.72e-13: 71.9: 22.50