HitPredict

Interactor 1: EXOS7 (Q15024)
Exosome complex component RRP42 (Exosome component 7) (Ribosomal RNA-processing protein 42) (p8)
Gene: EXOSC7

Interactor 2: MPH6 (Q99547)
M-phase phosphoprotein 6
Gene: MPHOSPH6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	28877463, 24981860, 33961781, 26186194, 28514442
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000178 - exosome (RNase complex) GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus and 1 others more... GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 291 Hs			1 160
+	Hs
		1284955 EXOS8_HUMAN (1-280): 1.58e-88: 266: 25.27		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		986713 EXOS9_HUMAN (1-289): 2.41e-76: 241: 25.77		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		110628 EXOS9_HUMAN (1-289): 2.41e-76: 241: 25.77		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00
+	Hs
		1304448 EXOS4_HUMAN (14-282): 5.34e-54: 177: 17.52		MPH6_HUMAN (1-160): 1.95e-67: 203: 100.00
+	Hs
		110631 EXOS4_HUMAN (14-282): 5.34e-54: 177: 17.52		H3BNT4_HUMAN (19-160): 1.34e-58: 180: 100.00