HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: POC1B (Q8TC44)
POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B)
Gene: POC1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 478
+	Hs
		161718 CUL4B_HUMAN (1-913): 0: 1185: 100.00		APAF_HUMAN (4-351): 2.98e-60: 215: 19.08
+	Hs
		1115343 CUL4B_HUMAN (1-913): 0: 1185: 100.00		FBXW7_HUMAN (171-456): 1.1e-54: 196: 16.50
+	Hs
		1114950 CUL4A_HUMAN (161-913): 0: 957: 81.83		POC1B_HUMAN (1-478): 4.29e-143: 420: 100.00
+	Hs
		1115406 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL1R_HUMAN (1-133): 2.55e-32: 131: 25.35
+	Hs
		964929 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5_HUMAN (300-443): 1.63e-23: 102: 9.59
+	Hs
		1115283 CUL4B_HUMAN (1-913): 0: 1185: 100.00		WDR5B_HUMAN (299-443): 8.68e-23: 100: 7.48
+	Hs
		845298 CUL4B_HUMAN (1-913): 0: 1185: 100.00		LIS1_HUMAN (313-471): 5.29e-22: 99.9: 9.32
+	Hs
		1115353 CUL4B_HUMAN (1-913): 0: 1185: 100.00		SNR40_HUMAN (312-444): 7.5e-19: 89.9: 8.09
+	Hs
		261407 CUL4B_HUMAN (1-913): 0: 1185: 100.00		TBL1X_HUMAN (303-443): 1.22e-10: 65.6: 7.01
+	Hs
		597359 CUL4A_HUMAN (161-913): 0: 957: 81.83		GBB3_HUMAN (6-172): 5.65e-35: 135: 24.71
+	Hs
		1115073 CUL4A_HUMAN (161-913): 0: 957: 81.83		GBB4_HUMAN (6-172): 2.12e-34: 133: 25.88
+	Hs
		161717 CUL3_HUMAN (186-913): 0: 854: 37.19		APAF_HUMAN (4-351): 2.98e-60: 215: 19.08
+	Hs
		964928 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5_HUMAN (300-443): 1.63e-23: 102: 9.59
+	Hs
		1114921 CUL4A_HUMAN (161-913): 0: 957: 81.83		WDR5B_HUMAN (299-443): 8.68e-23: 100: 7.48
+	Hs
		845297 CUL4A_HUMAN (161-913): 0: 957: 81.83		LIS1_HUMAN (313-471): 5.29e-22: 99.9: 9.32
+	Hs
		984104 CUL4A_HUMAN (161-913): 0: 957: 81.83		GBB2_HUMAN (180-358): 2.14e-19: 91.2: 16.39
+	Hs
		1114994 CUL4A_HUMAN (161-913): 0: 957: 81.83		SNR40_HUMAN (312-444): 7.5e-19: 89.9: 8.09
+	Hs
		209262 CUL3_HUMAN (186-913): 0: 854: 37.19		PRP4_HUMAN (214-417): 4.14e-25: 109: 17.29
+	Hs
		964927 CUL3_HUMAN (186-913): 0: 854: 37.19		WDR5_HUMAN (300-443): 1.63e-23: 102: 9.59
+	Hs
		984103 CUL3_HUMAN (186-913): 0: 854: 37.19		GBB2_HUMAN (180-358): 2.14e-19: 91.2: 16.39