HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: ZHX1 (Q9UKY1)
Zinc fingers and homeoboxes protein 1
Gene: ZHX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 873
+	Hs
		1159046 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		ZHX1_HUMAN (1-873): 0: 841: 100.00
+	Hs
		1066559 RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00		ZHX2_HUMAN (354-871): 1.71e-18: 92.9: 15.85
+	Hs
		790035 RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00		ZEB1_HUMAN (18-179): 9.42e-10: 64.8: 18.52
+	Hs
		245616 RBBP4_HUMAN (1-425): 2.89e-121: 360: 100.00		ZEB2_HUMAN (63-150): 2.56e-09: 63.3: 19.32
+	Hs
		1159035 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		DUX4_HUMAN (450-672): 5.81e-31: 128: 15.86
+	Hs
		1232400 Q6FHQ0_HUMAN (9-210): 1.64e-35: 137: 12.56		DUX4_HUMAN (450-672): 5.81e-31: 128: 15.86
+	Hs
		1159063 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		ZHX2_HUMAN (354-871): 1.71e-18: 92.9: 15.85
+	Hs
		245633 RBBP7_HUMAN (9-210): 1.64e-35: 137: 12.56		ZEB2_HUMAN (63-150): 2.56e-09: 63.3: 19.32