Protein: ZHX1
Zinc fingers and homeoboxes protein 1

Gene: ZHX1
Organism: Homo sapiens
Interactions: 100
UniProt ID: Q9UKY1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1446806

LHX9
LIM/homeobox protein Lhx9

3

20

High-throughput

0.861

High

1461322

ZHX1
Zinc fingers and homeoboxes protein 1

3

16

Small-scale

0.850

High

1461324

ZHX2
Zinc fingers and homeoboxes protein 2

2

17

Small-scale

0.776

High

155038

BHE40
Class E basic helix-loop-helix protein 40

1

1

High-throughput

0.698

High

1433684

ZHX3
Zinc fingers and homeoboxes protein 3

1

18

Small-scale

0.680

High

927606

ATX1
Ataxin-1

3

7

Small-scale

0.675

High

1146270

ZMY11
Zinc finger MYND domain-containing protein 11

3

14

Small-scale

0.645

High

1412047

WDR83
WD repeat domain-containing protein 83

4

4

High-throughput

0.630

High

659712

NFYA
Nuclear transcription factor Y subunit alpha

2

1

Small-scale

0.622

High

605226

TAL1
T-cell acute lymphocytic leukemia protein 1

1

5

High-throughput

0.621

High

993807

UBC9
SUMO-conjugating enzyme UBC9

2

1

Small-scale

0.619

High

210143

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.618

High

685386

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.618

High

1379965

LHX4
LIM/homeobox protein Lhx4

1

20

High-throughput

0.618

High

1458646

LHX3
LIM/homeobox protein Lhx3

1

20

High-throughput

0.618

High

675720

TYY1
Transcriptional repressor protein YY1

2

9

High-throughput

0.611

High

1066544

RBBP4
Histone-binding protein RBBP4

2

8

High-throughput

0.611

High

474363

NFIC
Nuclear factor 1 C-type

2

20

High-throughput

0.584

High

1458298

DNM3B
DNA

1

1

Small-scale

0.573

High

397190

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

991763

DYL1
Dynein light chain 1, cytoplasmic

1

3

High-throughput

0.541

High

998102

CSK21
Casein kinase II subunit alpha

1

8

High-throughput

0.541

High

1096269

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.541

High

1421327

WDR33
pre-mRNA 3' end processing protein WDR33

1

5

High-throughput

0.541

High

74641

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

2

High-throughput

0.536

High

336243

ZIC2
Zinc finger protein ZIC 2

1

6

High-throughput

0.536

High

1110179

HDAC1
Histone deacetylase 1

1

14

High-throughput

0.536

High

1368201

HDAC2
Histone deacetylase 2

1

14

High-throughput

0.536

High

1385982

ZN653
Zinc finger protein 653

1

4

High-throughput

0.536

High

128078

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.518

High

278992

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.518

High

593243

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.518

High

788259

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.518

High

838920

AK1C3
Aldo-keto reductase family 1 member C3

1

0

High-throughput

0.518

High

895507

SPB9
Serpin B9

1

0

High-throughput

0.518

High

928584

TERF1
Telomeric repeat-binding factor 1

1

0

High-throughput

0.518

High

1117163

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.518

High

1142469

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.518

High

1405173

MPH6
M-phase phosphoprotein 6

1

0

High-throughput

0.518

High

1447641

SAS10
Something about silencing protein 10

1

0

High-throughput

0.518

High

1451819

LYAR
Cell growth-regulating nucleolar protein

1

0

High-throughput

0.518

High

844082

HD
Huntingtin

1

1

High-throughput

0.515

High

1411751

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.513

High

280867

PR40A
Pre-mRNA-processing factor 40 homolog A

1

4

High-throughput

0.508

High

891876

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.508

High

1088614

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

14

High-throughput

0.508

High

1324612

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

High-throughput

0.508

High

1406804

BARD1
BRCA1-associated RING domain protein 1

1

5

High-throughput

0.508

High

508815

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.501

High

164970

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

1

High-throughput

0.494

High

964195

GBG11

1

1

High-throughput

0.494

High

665292

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.486

High

728476

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.486

High

1056678

ZN33B
Zinc finger protein 33B

1

0

High-throughput

0.486

High

354264

ZBED1
E3 SUMO-protein ligase ZBED1

1

1

Small-scale

0.481

High

414822

P53
Cellular tumor antigen p53

1

3

High-throughput

0.481

High

964507

SUMO2
Small ubiquitin-related modifier 2

1

8

Small-scale

0.481

High

991460

SUMO1
Small ubiquitin-related modifier 1

1

8

Small-scale

0.481

High

1156243

ZYX
Zyxin

1

1

Small-scale

0.481

High

1368526

CBP
CREB-binding protein

1

20

Small-scale

0.481

High

143319

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

339887

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.479

High

404535

GCR
Glucocorticoid receptor

1

15

High-throughput

0.479

High

776150

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

799569

BRCA1
Breast cancer type 1 susceptibility protein

1

8

High-throughput

0.479

High

834086

HNF4A
Hepatocyte nuclear factor 4-alpha

1

10

High-throughput

0.479

High

837105

ELK3
ETS domain-containing protein Elk-3

1

17

High-throughput

0.479

High

920353

PLK1
Serine/threonine-protein kinase PLK1

1

3

High-throughput

0.479

High

944762

KLF3
Krueppel-like factor 3

1

20

High-throughput

0.479

High

995341

CSK2B
Casein kinase II subunit beta

1

7

High-throughput

0.479

High

1017291

H33
Histone H3.3

1

7

High-throughput

0.479

High

1040090

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.479

High

1088091

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1133728

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1159046

RBBP7
Histone-binding protein RBBP7

1

8

High-throughput

0.479

High

1244843

FBX38
F-box only protein 38

1

1

High-throughput

0.479

High

1339028

NUP43
Nucleoporin Nup43

1

16

High-throughput

0.479

High

1405455

FEV
Protein FEV

1

17

High-throughput

0.479

High

1405651

ELF4
ETS-related transcription factor Elf-4

1

17

High-throughput

0.479

High

1416948

KLF16
Krueppel-like factor 16

1

18

High-throughput

0.479

High

1460383

KLF15
Krueppel-like factor 15

1

20

High-throughput

0.479

High

1461323

KLF12
Krueppel-like factor 12

1

20

High-throughput

0.479

High

475057

VIME
Vimentin

1

8

High-throughput

0.464

High

936627

ELL
RNA polymerase II elongation factor ELL

1

0

Small-scale

0.460

High

660190

COF1
Cofilin-1

1

0

High-throughput

0.458

High

1118189

DX39B
Spliceosome RNA helicase DDX39B

1

9

Small-scale

0.457

High

791041

TALDO
Transaldolase

1

0

High-throughput

0.438

High

158717

GBGT2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2

1

1

High-throughput

0.437

High

296078

IDHC
Isocitrate dehydrogenase [NADP] cytoplasmic

1

0

High-throughput

0.282

High

361827

PNPH
Purine nucleoside phosphorylase

1

0

High-throughput

0.282

High

639656

SAT1
Diamine acetyltransferase 1

1

0

High-throughput

0.282

High

963034

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.282

High

1157285

LAMA4
Laminin subunit alpha-4

1

0

High-throughput

0.282

High

1363775

PIGC
Phosphatidylinositol N-acetylglucosaminyltransferase subunit C

1

0

High-throughput

0.282

High

1429881

TOLIP
Toll-interacting protein

1

0

High-throughput

0.282

High

867502

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.279

Low

939664

BID
BH3-interacting domain death agonist

1

0

High-throughput

0.265

Low

1060245

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.265

Low

231349

EFNA2
Ephrin-A2

1

0

Small-scale

0.251

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025