Interactor 1: PDK1 (Q15118)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 1) (PDH kinase 1)
Gene: PDK1
Interactor 2: PDK2 (Q15119)
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 2) (PDH kinase 2) (PDKII)
Gene: PDK2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 1.00 | 0.964 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 26496610, 28514442, 29568061, 12573248, 33961781, 32707033 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BCDHK_Adom3~HATPase_c, HATPase_c~HATPase_c |
| Common GO terms | GO:0004672 - protein kinase activity GO:0004740 - pyruvate dehydrogenase (acetyl-transferring) kinase activity GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix and 4 others more... |
| Homologous interactions | 11 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
