Interactor 1: NADC (Q15274)
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase)
Gene: QPRT

Interactor 2: NADC (Q15274)
Nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) (Quinolinate phosphoribosyltransferase [decarboxylating]) (QAPRTase) (QPRTase)
Gene: QPRT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.845

The method score is based on:

Property Details
Experiments 25416956, 32296183, unassigned1304
Identification Methods two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains QRPTase_C~QRPTase_C, QRPTase_C~QRPTase_N, QRPTase_N~QRPTase_N
Common GO terms GO:0004514 - nicotinate-nucleotide diphosphorylase (carboxylating) activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0009435 - NAD biosynthetic process
GO:0019674 - NAD metabolic process
and 3 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 297
Hs

1 297
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024