HitPredict

Interactor 1: HIF1 (G5EGD2)
Hypoxia-inducible factor 1 (Hypoxia-induced factor 1)
Gene: hif-1

Interactor 2: NHR62 (O02279)
Nuclear hormone receptor family member nhr-62
Gene: nhr-62

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	23791784
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 719 Ce			1 515
+	Ce
		106934 HIF1_CAEEL (1-719): 0: 731: 100.00		NH114_CAEEL (84-511): 8.12e-100: 308: 19.31
+	Ce
		108084 HIF1_CAEEL (1-719): 0: 731: 100.00		H2KZU3_CAEEL (73-504): 1.52e-87: 277: 33.26
+	Ce
		108085 HIF1_CAEEL (1-719): 0: 731: 100.00		H2KZU4_CAEEL (73-504): 4.85e-87: 276: 32.30
+	Ce
		108122 HIF1_CAEEL (1-719): 0: 731: 100.00		Q86PI8_CAEEL (86-371): 2.93e-77: 246: 22.87
+	Ce
		108116 HIF1_CAEEL (1-719): 0: 731: 100.00		Q21372_CAEEL (98-319): 1.05e-26: 114: 33.18
+	Hs
		126103 BMAL1_HUMAN (4-530): 3.58e-129: 398: 15.16		RXRA_HUMAN (2-512): 1.38e-114: 348: 16.79
+	Hs
		369025 ARNT_HUMAN (2-560): 2.82e-131: 408: 18.03		ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63
+	Hs
		369703 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63
+	Hs
		370292 EPAS1_HUMAN (2-466): 7.27e-124: 391: 22.67		ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63
+	Hs
		126099 BMAL1_HUMAN (4-530): 3.58e-129: 398: 15.16		RARA_HUMAN (20-514): 1.31e-91: 289: 16.27
+	Hs
		914652 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		ERR3_HUMAN (6-506): 1.09e-87: 278: 16.77
+	Hs
		649056 ARNT_HUMAN (2-560): 2.82e-131: 408: 18.03		HNF4A_HUMAN (45-510): 2.94e-85: 272: 19.74
+	Hs
		782560 HIF1A_HUMAN (2-488): 5.69e-130: 406: 24.71		HNF4A_HUMAN (45-510): 2.94e-85: 272: 19.74
+	Mm
		864788 ARNT_MOUSE (2-622): 1.01e-125: 394: 16.81		ERR3_MOUSE (6-506): 1.09e-87: 278: 16.77
+	Hs
		126108 BMAL1_HUMAN (4-530): 3.58e-129: 398: 15.16		HNF4A_HUMAN (45-510): 2.94e-85: 272: 19.74
+	Mm
		914681 EPAS1_MOUSE (2-604): 1.09e-119: 381: 18.69		ERR3_MOUSE (6-506): 1.09e-87: 278: 16.77
+	Hs
		369684 NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78		ESR1_HUMAN (22-513): 1.55e-101: 319: 15.63
+	Hs
		130328 NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78		NR5A2_HUMAN (1-506): 1.12e-101: 317: 14.93
+	Hs
		490063 NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78		NR2F6_HUMAN (64-515): 2.72e-94: 294: 19.03
+	Hs
		487978 NCOA1_HUMAN (2-575): 3.99e-99: 335: 14.78		RARA_HUMAN (20-514): 1.31e-91: 289: 16.27