HitPredict

Interactor 1: DDB1 (Q16531)
DNA damage-binding protein 1 (DDB p127 subunit) (DNA damage-binding protein a) (DDBa) (Damage-specific DNA-binding protein 1) (HBV X-associated protein 1) (XAP-1) (UV-damaged DNA-binding factor) (UV-damaged DNA-binding protein 1) (UV-DDB 1) (XPE-binding factor) (XPE-BF) (Xeroderma pigmentosum group E-complementing protein) (XPCe)
Gene: DDB1

Interactor 2: DCA12 (Q5T6F0)
DDB1- and CUL4-associated factor 12 (Centrosome-related protein TCC52) (Testis cancer centrosome-related protein) (WD repeat-containing protein 40A)
Gene: DCAF12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.915

Property	Details
Experiments	16949367, 35271311, 36715408, 16964240, 19966799
Identification Methods	affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 453
+	Mm
		1112267 DDB1_MOUSE (1-1140): 0: 1422: 99.65		DCA12_MOUSE (1-453): 0: 813: 98.46
+	Dm
		1366011 DDB1_DROME (1-1140): 0: 1237: 60.84		DCA12_DROME (3-452): 0: 607: 39.65