HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 425 Hs			1 126
+	Hs
		267752 TAF5L_HUMAN (32-291): 7.24e-42: 157: 16.48		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		918317 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21
+	Hs
		997744 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		707605 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	Hs
		420817 WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61		H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21
+	Hs
		903263 WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61		H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00
+	Hs
		707570 WDR5_HUMAN (311-425): 1.28e-17: 85.2: 22.61		H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41
+	At
		189120 GBLPA_ARATH (80-300): 3.3e-15: 78.2: 13.67		H2B1_ARATH (3-125): 2.03e-43: 141: 68.80
+	Sc
		355898 HAT2_YEAST (224-421): 1.82e-19: 91.5: 11.88		H2B2_YEAST (3-125): 4.73e-37: 124: 71.55
+	Sc
		355487 HAT2_YEAST (224-421): 1.82e-19: 91.5: 11.88		H2B1_YEAST (3-125): 1.81e-36: 122: 71.55