HitPredict

Interactor 1: RBBP7 (Q16576)
Histone-binding protein RBBP7 (Histone acetyltransferase type B subunit 2) (Nucleosome-remodeling factor subunit RBAP46) (Retinoblastoma-binding protein 7) (RBBP-7) (Retinoblastoma-binding protein p46)
Gene: RBBP7

Interactor 2: PHF12 (Q96QT6)
PHD finger protein 12 (PHD factor 1) (Pf1)
Gene: PHF12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.733

Property	Details
Experiments	26496610, 26841866, 24981860, 26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 1004
+	Hs
		997864 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		PHF12_HUMAN (1-1004): 0: 1360: 100.00
+	Hs
		1083425 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		BAZ2B_HUMAN (3-239): 3.57e-37: 154: 17.07
+	Hs
		1017306 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28
+	Hs
		1083322 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77
+	Hs
		1059641 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Hs
		1018507 RBBP7_HUMAN (1-425): 2.38e-115: 345: 100.00		CHD3_HUMAN (11-166): 1.58e-19: 97.3: 16.96
+	Hs
		1346964 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		BAZ2B_HUMAN (3-239): 3.57e-37: 154: 17.07
+	Hs
		1346965 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		BAZ2A_HUMAN (2-240): 1.87e-29: 129: 16.33
+	Hs
		997694 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		BPTF_HUMAN (43-264): 2.26e-31: 135: 19.28
+	Dm
		332768 CAF1_DROME (1-209): 8.04e-42: 154: 13.16		CHDM_DROME (50-278): 8.02e-29: 127: 16.47
+	Dm
		1099182 CAF1_DROME (1-209): 8.04e-42: 154: 13.16		NU301_DROME (49-202): 9.45e-27: 120: 25.28
+	Hs
		1302684 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		RSF1_HUMAN (53-191): 9.33e-24: 110: 21.66
+	Hs
		1018714 NLE1_HUMAN (202-424): 3.82e-45: 164: 21.15		CHD3_HUMAN (11-166): 1.58e-19: 97.3: 16.96
+	Ce
		954000 LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16		CHD3_CAEEL (6-278): 1.12e-22: 107: 14.05
+	Ce
		104626 LIN53_CAEEL (1-209): 6.74e-42: 154: 14.16		LE418_CAEEL (6-278): 1.56e-20: 100: 14.29
+	Hs
		997824 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		CHD5_HUMAN (15-166): 1.47e-20: 100: 16.77
+	Hs
		997726 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Hs
		997695 RBBP4_HUMAN (1-209): 1.59e-39: 148: 12.72		CHD3_HUMAN (11-166): 1.58e-19: 97.3: 16.96
+	Hs
		929464 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		CHD4_HUMAN (52-166): 3.04e-20: 99.6: 19.23
+	Hs
		929424 RACK1_HUMAN (213-405): 2.23e-28: 115: 20.41		CHD3_HUMAN (11-166): 1.58e-19: 97.3: 16.96