Protein: MPE1
Protein MPE1

Gene: MPE1
Organism: Saccharomyces cerevisiae S288C
Interactions: 68
UniProt ID: P35728

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005847 - mRNA cleavage and polyadenylation specificity factor complex
GO:0006369 - termination of RNA polymerase II transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

776498

YSH1
Endoribonuclease YSH1

10

3

Small-scale

0.977

High

776499

CFT1
Protein CFT1

8

1

Small-scale

0.752

High

712916

PAP
Poly(A) polymerase

8

1

Small-scale

0.750

High

776503

CFT2
Cleavage factor two protein 2

8

3

Small-scale

0.749

High

776478

PFS2
Polyadenylation factor subunit 2

7

2

Small-scale

0.745

High

776463

SWD2
COMPASS component SWD2

6

2

Small-scale

0.732

High

776497

YTH1
mRNA 3'-end-processing protein YTH1

6

1

Small-scale

0.730

High

776490

PTA1
Pre-tRNA-processing protein PTA1

11

0

Small-scale

0.724

High

776477

REF2
RNA end formation protein 2

7

0

Small-scale

0.714

High

776480

FIP1
Pre-mRNA polyadenylation factor FIP1

7

0

Small-scale

0.713

High

743178

PP12
Serine/threonine-protein phosphatase PP1-2

5

0

Small-scale

0.679

High

671409

RNA14
mRNA 3'-end-processing protein RNA14

3

1

Small-scale

0.671

High

776468

PTI1
Protein PTI1

4

0

Small-scale

0.661

High

776488

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

3

0

Small-scale

0.628

High

776467

PCF11
Protein PCF11

2

0

High-throughput

0.595

High

749655

TYE7
Transcription factor TYE7

2

0

High-throughput

0.563

High

776469

IF4F2
Eukaryotic initiation factor 4F subunit p130

2

1

High-throughput

0.537

High

433001

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.536

High

671447

RNA15
mRNA 3'-end-processing protein RNA15

1

3

Small-scale

0.536

High

585699

UBC4
Ubiquitin-conjugating enzyme E2 4

1

0

Small-scale

0.480

High

706741

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

776482

JHD2
Histone demethylase JHD2

1

1

Small-scale

0.479

High

776495

GIS1
Transcriptional activator/repressor GIS1

1

1

High-throughput

0.479

High

655618

TAF2
Transcription initiation factor TFIID subunit 2

1

0

High-throughput

0.458

High

758196

URB1
Nucleolar pre-ribosomal-associated protein 1

1

0

High-throughput

0.458

High

776474

PSF2
DNA replication complex GINS protein PSF2

1

0

Small-scale

0.458

High

776481

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

776504

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

736172

RNP1
Ribonucleoprotein 1

1

2

High-throughput

0.457

High

776508

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

1

High-throughput

0.457

High

403445

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

1

High-throughput

0.445

High

544410

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

776470

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

776472

RL13B
Large ribosomal subunit protein eL13B

1

1

High-throughput

0.445

High

776491

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.445

High

726137

2AAA
Protein phosphatase PP2A regulatory subunit A

1

0

High-throughput

0.438

High

734544

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.438

High

776466

VPS45
Vacuolar protein sorting-associated protein 45

1

0

High-throughput

0.438

High

776473

RFC2
Replication factor C subunit 2

1

0

High-throughput

0.438

High

776475

HAC1
Transcriptional activator HAC1

1

0

High-throughput

0.438

High

776483

YJ9I
Uncharacterized protein YJR141W

1

0

High-throughput

0.438

High

776489

CBK1
Serine/threonine-protein kinase CBK1

1

0

High-throughput

0.438

High

776505

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

High-throughput

0.438

High

444483

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.426

High

526366

HSP72
Heat shock protein SSA2

1

0

High-throughput

0.426

High

776476

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.426

High

776484

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

776493

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.417

High

776494

CEF1
Pre-mRNA-splicing factor CEF1

1

1

High-throughput

0.417

High

592163

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

150374

YP089
Dilute domain-containing protein YPR089W

1

0

High-throughput

0.238

Low

457150

PT494
COX3 mRNA-specific translational activator PET494

1

0

High-throughput

0.238

Low

577010

CBP7
Cytochrome B translational activator CBS2

1

0

High-throughput

0.238

Low

702302

MGLL
Monoglyceride lipase

1

0

High-throughput

0.238

Low

776464

PAU24
Seripauperin-24

1

0

High-throughput

0.238

Low

776465

CTPP1
Lipid-anchored plasma membrane protein CPP1

1

0

High-throughput

0.238

Low

776471

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.238

Low

776479

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.238

Low

776486

YIP4
Protein YIP4

1

0

High-throughput

0.238

Low

776487

VSB1
Vacuolar basic amino acid transporter VSB1

1

0

High-throughput

0.238

Low

776492

YP039
Uncharacterized protein YPL039W

1

0

High-throughput

0.238

Low

776496

ERV41
ER-derived vesicles protein ERV41

1

0

High-throughput

0.238

Low

776500

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.238

Low

776501

IRC23
Increased recombination centers protein 23

1

0

High-throughput

0.238

Low

776502

YP204
Y' element ATP-dependent helicase YPR204W

1

0

High-throughput

0.238

Low

776506

IRC16
Uncharacterized protein IRC16

1

0

High-throughput

0.238

Low

776507

YM158
Putative uncharacterized protein YMR158W-B

1

0

High-throughput

0.238

Low

776485

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025