HitPredict

Interactor 1: DREB (Q16643)
Drebrin (Developmentally-regulated brain protein)
Gene: DBN1

Interactor 2: MYO6 (Q9UM54)
Unconventional myosin-VI (Unconventional myosin-6)
Gene: MYO6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005884 - actin filament GO:0007015 - actin filament organization GO:0015629 - actin cytoskeleton and 1 others more... GO:0051015 - actin filament binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 649 Hs			1 1294
+	Hs
		203261 SYNJ1_HUMAN (103-518): 1.79e-09: 63.3: 9.35		MYO6_HUMAN (1-1294): 0: 1083: 100.00
+	Ce
		136791 UNC89_CAEEL (117-542): 8.63e-34: 141: 12.70		HUM6_CAEEL (1-895): 0: 875: 31.42
+	Hs
		1085071 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		MYO5C_HUMAN (772-1230): 2.22e-24: 113: 9.42
+	Hs
		724849 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70
+	Hs
		1085096 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		MYO5B_HUMAN (1016-1294): 4.73e-09: 63.4: 12.41
+	Hs
		1085107 DREB_HUMAN (1-649): 5.59e-95: 307: 100.00		MYO5A_HUMAN (595-1063): 4.98e-09: 63: 10.72
+	Hs
		724893 MICA3_HUMAN (205-642): 2.69e-09: 62.9: 11.11		MYH9_HUMAN (842-1118): 6.25e-10: 66.2: 14.70