HitPredict

Interactor 1: DGKD (Q16760)
Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta)
Gene: DGKD

Interactor 2: DGKD (Q16760)
Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta)
Gene: DGKD

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.813

The method score is based on:

Property Details
Experiments 12200442, 18334213
Identification Methods affinity chromatography technology, 3D electron microscopy, molecular sieving, x-ray crystallography, surface plasmon resonance, cosedimentation in solution
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C1_1~C1_1, C1_1~PH, DAGK_cat~DAGK_cat, PH~PH, SAM_2~SAM_2
Common GO terms GO:0004143 - ATP-dependent diacylglycerol kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 20 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 1214
Hs

1 1214
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Last updated: 15 Jul 2024