HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~Rtt106
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006334 - nucleosome assembly
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1047
+	Hs
		1274488 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		420898 H2B1J_HUMAN (1-126): 7.8e-54: 166: 99.21		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		918796 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		707803 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1231268 H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Hs
		1282986 H2B1A_HUMAN (1-126): 3.43e-46: 147: 85.04		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Sc
		355829 H2B2_YEAST (3-125): 4.73e-37: 124: 71.55		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Sc
		355400 H2B1_YEAST (3-125): 1.81e-36: 122: 71.55		SPT16_YEAST (3-1008): 0: 938: 33.49