Protein: DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing] (pDCR) (EC 1.3.1.124) (2,4-dienoyl-CoA reductase 2) (Short chain dehydrogenase/reductase family 17C member 1)

Gene: DECR2
Organism: Homo sapiens
Interactions: 65
UniProt ID: Q9NUI1

Gene Ontology (top 5):
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005829 - cytosol
GO:0006631 - fatty acid metabolic process
GO:0006636 - unsaturated fatty acid biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

896314

PEX5
Peroxisomal targeting signal 1 receptor

3

3

Small-scale

0.631

High

1212242

NHRF3
Na(+)/H(+) exchange regulatory cofactor NHE-RF3

2

3

High-throughput

0.611

High

907599

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

2

0

High-throughput

0.580

High

1449837

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.580

High

397037

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

593511

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

977594

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

1

High-throughput

0.536

High

1327607

WDTC1
WD and tetratricopeptide repeats protein 1

1

2

High-throughput

0.536

High

292936

RNH2A
Ribonuclease H2 subunit A

1

0

High-throughput

0.513

High

1292417

OSTM1
Osteopetrosis-associated transmembrane protein 1

1

0

High-throughput

0.513

High

1359160

GLMP
Glycosylated lysosomal membrane protein

1

0

High-throughput

0.513

High

1430301

GBP3
Guanylate-binding protein 3

1

0

High-throughput

0.513

High

1449840

LIMA1
LIM domain and actin-binding protein 1

1

0

High-throughput

0.513

High

423290

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

1400032

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

2

High-throughput

0.501

High

1380866

TRI63
E3 ubiquitin-protein ligase TRIM63

1

8

High-throughput

0.494

High

1419306

TRI55
Tripartite motif-containing protein 55

1

8

High-throughput

0.494

High

260973

RAMP3
Receptor activity-modifying protein 3

1

1

High-throughput

0.489

High

774662

BASI
Basigin

1

1

High-throughput

0.489

High

922844

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

1

High-throughput

0.489

High

1435159

ESRP2
Epithelial splicing regulatory protein 2

1

1

High-throughput

0.489

High

1436699

GORS2
Golgi reassembly-stacking protein 2

1

1

High-throughput

0.489

High

508703

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

122562

ADAS
Alkyldihydroxyacetonephosphate synthase, peroxisomal

1

1

High-throughput

0.479

High

400029

CATA
Catalase

1

2

High-throughput

0.479

High

401561

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

867452

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

1026557

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

1089271

TRI26
Tripartite motif-containing protein 26

1

3

Small-scale

0.479

High

1383408

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

2

High-throughput

0.479

High

1449839

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.479

High

1067760

EP300
Histone acetyltransferase p300

1

0

High-throughput

0.460

High

831508

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

1429991

SHRPN
Sharpin

1

0

Small-scale

0.458

High

1227546

A16L1
Autophagy-related protein 16-1

1

4

High-throughput

0.445

High

1414651

TCAB1
Telomerase Cajal body protein 1

1

1

High-throughput

0.445

High

294401

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

1151899

RHOH
Rho-related GTP-binding protein RhoH

1

1

High-throughput

0.437

High

1255744

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

1367386

ESR2
Estrogen receptor beta

1

7

High-throughput

0.437

High

890685

RGS3
Regulator of G-protein signaling 3

1

0

High-throughput

0.426

High

921574

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

0

High-throughput

0.426

High

71067

PDZ1P
Putative PDZ domain-containing protein PDZK1P1

1

3

High-throughput

0.407

High

538813

GTR2
Solute carrier family 2, facilitated glucose transporter member 2

1

4

High-throughput

0.407

High

652258

GTR5
Solute carrier family 2, facilitated glucose transporter member 5

1

4

High-throughput

0.407

High

1063879

LG3BP
Galectin-3-binding protein

1

3

High-throughput

0.407

High

1150492

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

1

3

High-throughput

0.407

High

1155042

ADIPO
Adiponectin

1

1

High-throughput

0.407

High

1410912

GORS1
Golgi reassembly-stacking protein 1

1

1

High-throughput

0.407

High

1446075

S39A2
Zinc transporter ZIP2

1

1

High-throughput

0.407

High

171109

VP26C
Vacuolar protein sorting-associated protein 26C

2

0

High-throughput

0.316

High

1449841

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

1291743

SESD1
SEC14 domain and spectrin repeat-containing protein 1

2

0

High-throughput

0.313

High

166057

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

565722

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

0

High-throughput

0.279

Low

700807

DMB
HLA class II histocompatibility antigen, DM beta chain

1

0

High-throughput

0.279

Low

1032669

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

0

High-throughput

0.279

Low

1218866

GP107
Protein GPR107

1

0

High-throughput

0.279

Low

1325931

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.279

Low

1358914

SEN15
tRNA-splicing endonuclease subunit Sen15

1

0

High-throughput

0.279

Low

1432880

TMPS5
Transmembrane protease serine 5

1

0

High-throughput

0.279

Low

1449842

GPR45
Probable G-protein coupled receptor 45

1

0

High-throughput

0.279

Low

1115093

CUL4A
Cullin-4A

1

0

High-throughput

0.249

Low

1449838

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.249

Low

1449276

S22AB
Solute carrier family 22 member 11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025