HitPredict

Interactor 1: PTN21 (Q16825)
Tyrosine-protein phosphatase non-receptor type 21 (EC 3.1.3.48) (Protein-tyrosine phosphatase D1)
Gene: PTPN21

Interactor 2: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27880917, 27432908
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1174 Hs			1 1192
+	Hs
		1076877 PTN14_HUMAN (3-1174): 0: 813: 52.54		WWC2_HUMAN (1-1192): 0: 1008: 100.00
+	Hs
		1087910 PTN21_HUMAN (1-1174): 0: 888: 100.00		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		1076894 PTN14_HUMAN (3-1174): 0: 813: 52.54		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		299270 FARP2_HUMAN (16-539): 4.06e-131: 428: 21.17		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		1220100 E41L3_HUMAN (15-899): 2.79e-124: 411: 16.94		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		204697 E41L2_HUMAN (7-542): 3.43e-125: 411: 23.99		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Dm
		1359212 Q9V3V3_DROME (1-1174): 3.31e-151: 488: 23.33		KIBRA_DROME (8-1190): 0: 661: 30.31
+	Hs
		1076909 PTN14_HUMAN (3-1174): 0: 813: 52.54		MAGI1_HUMAN (1-300): 2.32e-62: 236: 18.94
+	Hs
		1087931 PTN21_HUMAN (1-1174): 0: 888: 100.00		WWP1_HUMAN (6-136): 2.07e-35: 148: 23.78
+	Hs
		1076933 PTN14_HUMAN (3-1174): 0: 813: 52.54		WWOX_HUMAN (5-198): 5.51e-47: 176: 21.11
+	Hs
		1076918 PTN14_HUMAN (3-1174): 0: 813: 52.54		WWP1_HUMAN (6-136): 2.07e-35: 148: 23.78
+	Hs
		1076872 PTN14_HUMAN (3-1174): 0: 813: 52.54		MAGI3_HUMAN (9-97): 1.18e-34: 146: 43.82
+	Hs
		808660 PTN21_HUMAN (1-1174): 0: 888: 100.00		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25
+	Hs
		125485 PTN14_HUMAN (3-1174): 0: 813: 52.54		WWP2_HUMAN (3-143): 4.17e-30: 131: 23.84
+	Hs
		1076920 PTN14_HUMAN (3-1174): 0: 813: 52.54		SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82
+	Hs
		808641 PTN14_HUMAN (3-1174): 0: 813: 52.54		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25
+	Hs
		1238356 E41L5_HUMAN (18-664): 1.05e-118: 386: 20.18		SYT2_HUMAN (699-968): 1.49e-101: 330: 15.05
+	Dm
		1359218 Q9V3V3_DROME (1-1174): 3.31e-151: 488: 23.33		SUDX_DROME (3-302): 8.76e-48: 187: 20.07
+	Hs
		1336123 E41L3_HUMAN (15-899): 2.79e-124: 411: 16.94		SMUF1_HUMAN (40-194): 1.56e-14: 80.8: 16.49
+	Hs
		204630 E41L2_HUMAN (7-542): 3.43e-125: 411: 23.99		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25