Protein: MAML1
Mastermind-like protein 1 (Mam-1)

Gene: MAML1
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q92585

Gene Ontology (top 5):
GO:0002193 - MAML1-RBP-Jkappa- ICN1 complex
GO:0003162 - atrioventricular node development
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

857516

NOTC1
Neurogenic locus notch homolog protein 1

12

14

Small-scale

0.982

High

1054750

SUH
Recombining binding protein suppressor of hairless

12

4

Small-scale

0.980

High

1067552

EP300
Histone acetyltransferase p300

3

20

Small-scale

0.651

High

1047671

NOTC2
Neurogenic locus notch homolog protein 2

1

12

Small-scale

0.647

High

1365151

NOTC4
Neurogenic locus notch homolog protein 4

1

12

Small-scale

0.647

High

1365159

NOTC3
Neurogenic locus notch homolog protein 3

1

13

Small-scale

0.647

High

414318

P53
Cellular tumor antigen p53

2

9

Small-scale

0.624

High

143146

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

1087899

NFIA
Nuclear factor 1 A-type

2

20

High-throughput

0.584

High

396622

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1365157

HDAC9
Histone deacetylase 9

1

16

Small-scale

0.561

High

903435

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

14

High-throughput

0.536

High

1280369

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

10

High-throughput

0.536

High

1287962

PB1
Protein polybromo-1

1

11

High-throughput

0.536

High

1365154

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.536

High

1365160

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.536

High

1365155

RMD5A
E3 ubiquitin-protein transferase RMND5A

1

0

High-throughput

0.513

High

297660

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

Small-scale

0.501

High

881570

CDK8
Cyclin-dependent kinase 8

1

7

Small-scale

0.501

High

387135

TNNC2
Troponin C, skeletal muscle

1

1

High-throughput

0.489

High

698960

CALX
Calnexin

1

1

High-throughput

0.489

High

706242

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

173149

XPO1
Exportin-1

1

8

High-throughput

0.479

High

181544

TBXT
T-box transcription factor T

1

10

High-throughput

0.479

High

210068

CRX
Cone-rod homeobox protein

1

20

High-throughput

0.479

High

225073

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.479

High

341639

EYA4
Protein phosphatase EYA4

1

16

High-throughput

0.479

High

372717

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.479

High

378512

IL1A
Interleukin-1 alpha

1

3

Small-scale

0.479

High

404281

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

474160

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520236

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

538445

EGR2
E3 SUMO-protein ligase EGR2

1

6

High-throughput

0.479

High

540916

ERG
Transcriptional regulator ERG

1

20

High-throughput

0.479

High

662256

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

696082

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

725292

TLX1
T-cell leukemia homeobox protein 1

1

20

High-throughput

0.479

High

775892

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

776227

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

872588

SOX2
Transcription factor SOX-2

1

20

High-throughput

0.479

High

887064

CEBPA
CCAAT/enhancer-binding protein alpha

1

18

High-throughput

0.479

High

938486

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.479

High

962796

RND3
Rho-related GTP-binding protein RhoE

1

20

Small-scale

0.479

High

1033099

EWS
RNA-binding protein EWS

1

10

High-throughput

0.479

High

1048050

TLE3
Transducin-like enhancer protein 3

1

6

High-throughput

0.479

High

1056633

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

1103294

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.479

High

1118743

KLF5
Krueppel-like factor 5

1

19

High-throughput

0.479

High

1133562

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1150674

TRBP2
RISC-loading complex subunit TARBP2

1

9

Small-scale

0.479

High

1160877

TBR1
T-box brain protein 1

1

10

High-throughput

0.479

High

1276565

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

10

High-throughput

0.479

High

1314332

SLX4
Structure-specific endonuclease subunit SLX4

1

8

High-throughput

0.479

High

1316550

MAML2
Mastermind-like protein 2

1

11

Small-scale

0.479

High

1339115

NUP35
Nucleoporin NUP35

1

5

High-throughput

0.479

High

1351099

SP7
Transcription factor Sp7

1

16

High-throughput

0.479

High

1363926

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

3

High-throughput

0.479

High

1365149

CBP
CREB-binding protein

1

20

Small-scale

0.479

High

1365150

MAML3
Mastermind-like protein 3

1

11

Small-scale

0.479

High

1365152

FEV
Protein FEV

1

19

High-throughput

0.479

High

1365153

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1365156

KLF15
Krueppel-like factor 15

1

18

High-throughput

0.479

High

1365158

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

4

Small-scale

0.479

High

1244808

FBX38
F-box only protein 38

1

0

High-throughput

0.458

High

246818

KDM1A
Lysine-specific histone demethylase 1A

1

12

High-throughput

0.445

High

464707

CXB1
Gap junction beta-1 protein

1

1

Small-scale

0.437

High

1331230

ARL10
ADP-ribosylation factor-like protein 10

1

3

High-throughput

0.437

High

1365161

NINL
Ninein-like protein

1

9

High-throughput

0.437

High

321930

FRYL
Protein furry homolog-like

1

1

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025