HitPredict

Interactor 1: PTPRO (Q16827)
Receptor-type tyrosine-protein phosphatase O (R-PTP-O) (EC 3.1.3.48) (Glomerular epithelial protein 1) (Protein tyrosine phosphatase U2) (PTP-U2) (PTPase U2)
Gene: PTPRO

Interactor 2: TMX4 (Q9H1E5)
Thioredoxin-related transmembrane protein 4 (Thioredoxin domain-containing protein 13)
Gene: TMX4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27432908
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1216 Hs			1 349
+	Hs
		1087983 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		TMX1_HUMAN (37-241): 1.77e-64: 207: 43.42
+	Hs
		1067718 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA6_HUMAN (3-156): 4.69e-36: 137: 18.71
+	Hs
		671825 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA3_HUMAN (5-143): 3.25e-33: 130: 17.01
+	Hs
		423243 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA1_HUMAN (27-137): 2.54e-31: 125: 17.80
+	Hs
		1087956 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		DJC10_HUMAN (84-263): 3.65e-10: 63.4: 12.02
+	Hs
		531846 PTPRO_HUMAN (1-1216): 0: 2236: 100.00		PDIA4_HUMAN (127-276): 4.35e-10: 63: 10.26
+	Hs
		1295307 PTN18_HUMAN (919-1216): 2.35e-120: 382: 30.52		TMX3_HUMAN (36-299): 4.93e-45: 162: 17.78
+	Hs
		577042 PTPRA_HUMAN (922-1196): 1.24e-99: 337: 35.48		TXND5_HUMAN (7-268): 4.56e-58: 195: 19.10
+	Hs
		577022 PTPRA_HUMAN (922-1196): 1.24e-99: 337: 35.48		PDIA6_HUMAN (3-156): 4.69e-36: 137: 18.71
+	Hs
		660849 PTPRM_HUMAN (918-1199): 6.38e-60: 228: 27.95		PDIA6_HUMAN (3-156): 4.69e-36: 137: 18.71
+	Hs
		1067777 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA6_HUMAN (3-156): 4.69e-36: 137: 18.71
+	Hs
		671887 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA3_HUMAN (5-143): 3.25e-33: 130: 17.01
+	Hs
		423314 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA1_HUMAN (27-137): 2.54e-31: 125: 17.80
+	Hs
		660862 PTPRM_HUMAN (918-1199): 6.38e-60: 228: 27.95		DJC10_HUMAN (84-263): 3.65e-10: 63.4: 12.02
+	Hs
		1220443 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		DJC10_HUMAN (84-263): 3.65e-10: 63.4: 12.02
+	Hs
		531930 PTPRU_HUMAN (918-1200): 4.38e-58: 222: 29.63		PDIA4_HUMAN (127-276): 4.35e-10: 63: 10.26