HitPredict

Interactor 1: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Interactor 2: PTPRN (Q16849)
Receptor-type tyrosine-protein phosphatase-like N (R-PTP-N) (Islet cell antigen 512) (ICA 512) (Islet cell autoantigen 3) (PTP IA-2) [Cleaved into: ICA512-N-terminal fragment (ICA512-NTF); ICA512-transmembrane fragment (ICA512-TMF); ICA512-cleaved cytosolic fragment (ICA512-CCF)]
Gene: PTPRN

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.726

The method score is based on:

Property Details
Experiments 27432908, 15978577
Identification Methods affinity chromatography technology, tox-r dimerization assay
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Receptor_IA-2~Receptor_IA-2, Y_phosphatase~Y_phosphatase
Common GO terms GO:0000302 - response to reactive oxygen species
GO:0001553 - luteinization
GO:0005634 - nucleus
GO:0005768 - endosome
GO:0005794 - Golgi apparatus
and 16 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 979
Hs

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Last updated: 15 Jul 2024