Interactor 1: EZRI (P26040)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: Ezr

Interactor 2: MERL (P46662)
Merlin (Moesin-ezrin-radixin-like protein) (Neurofibromin-2) (Schwannomin)
Gene: Nf2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 15102471
Identification Methods two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ERM_C~ERM_C, ERM_C~FERM_C, ERM_C~FERM_M, ERM_helical~FERM_N, FERM_C~FERM_C, FERM_C~FERM_M, FERM_C~FERM_N, FERM_M~FERM_M, FERM_M~FERM_N, FERM_N~FERM_N
Common GO terms GO:0003779 - actin binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0005912 - adherens junction
GO:0008360 - regulation of cell shape
and 9 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 586
Mm

1 596
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Ce
+ Ce
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024