HitPredict

Interactor 1: LTC4S (Q16873)
Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Glutathione S-transferase LTC4) (EC 2.5.1.-) (Leukotriene-C(4) synthase) (Leukotriene-C4 synthase)
Gene: LTC4S

Interactor 2: LTC4S (Q16873)
Leukotriene C4 synthase (LTC4 synthase) (EC 4.4.1.20) (Glutathione S-transferase LTC4) (EC 2.5.1.-) (Leukotriene-C(4) synthase) (Leukotriene-C4 synthase)
Gene: LTC4S

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.921

The method score is based on:

Property Details
Experiments 19233132, 22139193, 17632546, 17632548, 15530365
Identification Methods fluorescent resonance energy transfer, x-ray crystallography, electron microscopy, molecular sieving
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MAPEG~MAPEG
Common GO terms GO:0004364 - glutathione transferase activity
GO:0004464 - leukotriene-C4 synthase activity
GO:0004602 - glutathione peroxidase activity
GO:0005635 - nuclear envelope
GO:0005640 - nuclear outer membrane
and 10 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 150
Hs

1 150
+ Hs
+ Rn
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024