HitPredict

Interactor 1: NMDE1 (Q12879)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A) (hNR2A)
Gene: GRIN2A

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	15254094
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008021 - synaptic vesicle GO:0098978 - glutamatergic synapse
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1464 Hs			1 435
+	Hs
		1088790 NMDE1_HUMAN (1-1464): 0: 1748: 100.00		AP1M1_HUMAN (2-434): 4.83e-171: 487: 38.85
+	Hs
		1098532 NMDE2_HUMAN (4-1464): 0: 1535: 52.95		AP2M1_HUMAN (1-435): 3.72e-180: 511: 100.00
+	Hs
		1098535 NMDE2_HUMAN (4-1464): 0: 1535: 52.95		AP1M1_HUMAN (2-434): 4.83e-171: 487: 38.85
+	Hs
		125837 NMDE2_HUMAN (4-1464): 0: 1535: 52.95		AP4M1_HUMAN (1-434): 7.9e-118: 353: 27.53
+	Rn
		623653 GRIA1_RAT (13-878): 0: 680: 19.24		AP2M1_RAT (1-435): 3.72e-180: 511: 100.00
+	Rn
		623703 GRIA3_RAT (4-873): 0: 662: 18.78		AP2M1_RAT (1-435): 3.72e-180: 511: 100.00
+	Rn
		623677 GRIA2_RAT (14-873): 0: 651: 18.08		AP2M1_RAT (1-435): 3.72e-180: 511: 100.00