Interactor 1: MKK4 (Q20347)
MAP kinase kinase mkk-4 (EC 2.7.12.2)
Gene: mkk-4

Interactor 2: JNK1 (Q8WQG9)
Stress-activated protein kinase jnk-1 (EC 2.7.11.24)
Gene: jnk-1

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 14704431
Identification Methods two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000165 - MAPK cascade
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0016310 - phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 363
Ce

1 463
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Rn
+ At
+ At
+ Hs
+ At
+ Mm
+ Hs
+ At
+ Hs
+ At
+ Ce
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024