Interactor 1: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Interactor 2: AAPK1 (Q13131)
5'-AMP-activated protein kinase catalytic subunit alpha-1 (AMPK subunit alpha-1) (EC 2.7.11.1) (Acetyl-CoA carboxylase kinase) (ACACA kinase) (Hydroxymethylglutaryl-CoA reductase kinase) (HMGCR kinase) (EC 2.7.11.31) (Tau-protein kinase PRKAA1) (EC 2.7.11.26)
Gene: PRKAA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 31839598, 20562859
Identification Methods cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains AdenylateSensor~Pkinase, AMPK_alpha_AID~Pkinase, Pkinase~Pkinase
Common GO terms GO:0000785 - chromatin
GO:0001666 - response to hypoxia
GO:0002842 - positive regulation of T cell mediated immune response to tumor cell
GO:0003682 - chromatin binding
GO:0004672 - protein kinase activity
and 83 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 559
Hs

1 559
+ Rn
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ Zm
+ Rn
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025