Interactor 1: AGRIN (O00468)
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment (C90); Agrin C-terminal 22 kDa fragment (C22)]
Gene: AGRN

Interactor 2: DAG1 (Q14118)
Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]
Gene: DAG1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.585

The method score is based on:

Property Details
Experiments 8205617, unassigned1793
Identification Methods far western blotting, cross-linking study
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002162 - dystroglycan binding
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region
GO:0005604 - basement membrane
GO:0005796 - Golgi lumen
and 4 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 2068
Hs

1 895
+ Gg
+ Hs
+ Gg
+ Hs
+ Mm
+ Mm
+ Mm
+ Dm
+ Dm

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Last updated: 15 Jul 2024