HitPredict

Interactor 1: ISWI (Q24368)
Chromatin-remodeling complex ATPase chain Iswi (EC 3.6.4.-) (CHRAC 140 kDa subunit) (Nucleosome-remodeling factor 140 kDa subunit) (NURF-140) (Protein imitation swi)
Gene: ISWI

Interactor 2: DPOE3 (Q9V444)
DNA polymerase epsilon subunit 3 (Chromatin accessibility complex 14kD protein) (Histone-fold protein CHRAC subunit)
Gene: Chrac-14

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	10856248, 11447119, 26549447
Identification Methods	biochemical, pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006338 - chromatin remodeling GO:0008623 - CHRAC GO:0031507 - heterochromatin formation
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1027 Dm			1 128
+	Hs
		229503 SMCA5_HUMAN (12-1027): 0: 955: 71.07		DPOE3_HUMAN (1-122): 3.88e-32: 112: 46.72
+	Hs
		658740 SMCA1_HUMAN (25-989): 0: 953: 72.05		DPOE3_HUMAN (1-122): 3.88e-32: 112: 46.72
+	Sc
		979818 ISW2_YEAST (2-1027): 0: 828: 45.36		DPB4_YEAST (5-127): 1.78e-26: 99.3: 22.22
+	Sc
		696252 STH1_YEAST (9-659): 2e-129: 427: 41.31		DPB4_YEAST (5-127): 1.78e-26: 99.3: 22.22