Interactor 1: CAF1 (Q24572)
Chromatin assembly factor 1 p55 subunit (CAF-1 p55 subunit) (CAF-1) (Nucleosome-remodeling factor 55 kDa subunit) (NURF-55)
Gene: Caf1-55

Interactor 2: HDAC1 (Q94517)
Histone deacetylase HDAC1 (HD) (EC 3.5.1.98)
Gene: HDAC1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.81 0.60 0.701

The method score is based on:

Property Details
Experiments 11124122, 12697833, 15516265, 27117189
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005700 - polytene chromosome
GO:0005737 - cytoplasm
GO:0006325 - chromatin organization
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 430
Dm

1 521
+ Ce
+ At
+ At
+ At
+ At
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024