HitPredict

Interactor 1: SRSF5 (Q13243)
Serine/arginine-rich splicing factor 5 (Delayed-early protein HRS) (Pre-mRNA-splicing factor SRP40) (Splicing factor, arginine/serine-rich 5)
Gene: SRSF5

Interactor 2: ZC3H3 (Q8IXZ2)
Zinc finger CCCH domain-containing protein 3 (Smad-interacting CPSF-like factor)
Gene: ZC3H3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~zf-CCCH
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 948
+	Hs
		1061048 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		ZC3H3_HUMAN (1-948): 0: 1272: 100.00
+	Hs
		1102014 PABP4_HUMAN (104-189): 2.67e-16: 80.1: 21.98		ZC3H3_HUMAN (1-948): 0: 1272: 100.00
+	Hs
		1313146 PABP3_HUMAN (98-189): 6.87e-15: 76.3: 18.56		ZC3H3_HUMAN (1-948): 0: 1272: 100.00
+	Hs
		340744 SRSF4_HUMAN (5-265): 3.79e-51: 176: 53.64		CPSF4_HUMAN (634-881): 8.34e-62: 212: 23.81
+	Hs
		340741 SRSF3_HUMAN (4-78): 1.86e-11: 62.8: 47.56		CPSF4_HUMAN (634-881): 8.34e-62: 212: 23.81
+	Hs
		1061055 SRSF1_HUMAN (2-170): 6.58e-57: 184: 43.68		ZC3H8_HUMAN (718-804): 1.85e-13: 74.1: 24.44
+	Hs
		1099159 SRSF5_HUMAN (1-240): 2.61e-54: 178: 100.00		ZC3H8_HUMAN (718-804): 1.85e-13: 74.1: 24.44
+	Hs
		1099435 SRSF6_HUMAN (5-184): 1.34e-48: 165: 61.96		ZC3H8_HUMAN (718-804): 1.85e-13: 74.1: 24.44
+	Sp
		1008989 SRP2_SCHPO (1-267): 5.29e-40: 144: 35.97		YTH1_SCHPO (625-762): 3.1e-18: 84.9: 23.45
+	Hs
		1016671 SRSF3_HUMAN (4-78): 1.86e-11: 62.8: 47.56		ZC3H4_HUMAN (653-820): 1.19e-20: 100: 20.93