HitPredict

Interactor 1: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Interactor 2: RBM15 (Q96T37)
RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15)
Gene: RBM15

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000381 - regulation of alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 344 Hs			1 977
+	Hs
		1099211 SRSF5_HUMAN (2-180): 3.8e-46: 160: 64.25		RBM15_HUMAN (1-977): 0: 578: 100.00
+	Hs
		1061087 SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65		PABP5_HUMAN (174-532): 7.37e-67: 231: 15.07
+	Hs
		506128 SRSF6_HUMAN (1-322): 1.01e-43: 155: 100.00		PAB4L_HUMAN (161-525): 3.2e-76: 256: 14.83
+	Hs
		1099010 SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22		PABP5_HUMAN (174-532): 7.37e-67: 231: 15.07
+	Sc
		403283 PABP_YEAST (3-190): 1.08e-31: 126: 17.50		PABP_YEAST (134-631): 3.15e-75: 260: 13.75
+	Sc
		403371 GBP2_YEAST (4-203): 4.82e-23: 100: 19.05		PABP_YEAST (134-631): 3.15e-75: 260: 13.75
+	Hs
		1197174 PAP1L_HUMAN (1-195): 2.78e-31: 126: 15.53		PABP5_HUMAN (174-532): 7.37e-67: 231: 15.07
+	Sc
		403624 NOP3_YEAST (3-326): 1.2e-19: 91.2: 19.94		PABP_YEAST (134-631): 3.15e-75: 260: 13.75
+	Hs
		550244 SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65		PABP1_HUMAN (364-542): 1.76e-31: 133: 20.00
+	Hs
		550447 RBM4_HUMAN (1-343): 1.67e-48: 168: 17.05		PABP1_HUMAN (364-542): 1.76e-31: 133: 20.00
+	Hs
		550259 SRSF9_HUMAN (3-222): 5.62e-49: 165: 34.22		PABP1_HUMAN (364-542): 1.76e-31: 133: 20.00
+	Hs
		1060952 SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65		ELAV2_HUMAN (360-536): 6.2e-16: 82.6: 22.34
+	Mm
		710979 TIA1_MOUSE (2-332): 5.16e-33: 128: 16.24		PABP1_MOUSE (364-542): 2.18e-31: 133: 20.00
+	Hs
		550311 PAP1L_HUMAN (1-195): 2.78e-31: 126: 15.53		PABP1_HUMAN (364-542): 1.76e-31: 133: 20.00
+	Mm
		1000098 SRSF1_MOUSE (3-188): 3.03e-54: 180: 36.65		TIAR_MOUSE (367-535): 1.72e-14: 78.7: 23.50
+	Hs
		1197178 PAP1L_HUMAN (1-195): 2.78e-31: 126: 15.53		PABP3_HUMAN (364-542): 3.96e-29: 126: 20.53
+	Hs
		1090214 SRSF6_HUMAN (1-322): 1.01e-43: 155: 100.00		ELAV2_HUMAN (360-536): 6.2e-16: 82.6: 22.34
+	Hs
		1099491 SRSF6_HUMAN (1-322): 1.01e-43: 155: 100.00		MINT_HUMAN (452-754): 1.39e-11: 71.1: 15.77
+	Mm
		915284 TIA1_MOUSE (2-332): 5.16e-33: 128: 16.24		ELAV1_MOUSE (361-534): 2.79e-16: 83: 22.22
+	Mm
		1000307 Q80ZW7_MOUSE (2-332): 1.6e-31: 123: 16.15		ELAV1_MOUSE (361-534): 2.79e-16: 83: 22.22