Protein: RBM15
RNA-binding protein 15 (One-twenty two protein 1) (RNA-binding motif protein 15)

Gene: RBM15
Organism: Homo sapiens
Interactions: 191
UniProt ID: Q96T37

Gene Ontology (top 5):
GO:0000381 - regulation of alternative mRNA splicing, via spliceosome
GO:0001510 - RNA methylation
GO:0001569 - branching involved in blood vessel morphogenesis
GO:0003723 - RNA binding
GO:0003729 - mRNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1336751

RB15B
Putative RNA-binding protein 15B

3

17

Small-scale

0.861

High

1006644

SRPK2
SRSF protein kinase 2

2

19

High-throughput

0.806

High

1290118

THOC4
THO complex subunit 4

2

15

Small-scale

0.754

High

340588

CNOT4
CCR4-NOT transcription complex subunit 4

1

1

Small-scale

0.724

High

478174

SNRPA
U1 small nuclear ribonucleoprotein A

1

20

High-throughput

0.691

High

889796

CLK3
Dual specificity protein kinase CLK3

1

19

High-throughput

0.691

High

1115943

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

12

High-throughput

0.691

High

1160260

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

17

High-throughput

0.691

High

372921

MYC
Myc proto-oncogene protein

4

15

High-throughput

0.686

High

1403296

NXF1
Nuclear RNA export factor 1

3

4

Small-scale

0.676

High

1290667

ZCH18
Zinc finger CCCH domain-containing protein 18

3

8

High-throughput

0.667

High

1403295

SPN90
NCK-interacting protein with SH3 domain

3

1

High-throughput

0.662

High

853728

MK08
Mitogen-activated protein kinase 8

1

9

High-throughput

0.656

High

889488

CLK1
Dual specificity protein kinase CLK1

1

19

High-throughput

0.647

High

1369355

DDX17
Probable ATP-dependent RNA helicase DDX17

2

6

High-throughput

0.633

High

1308812

NAV2
Neuron navigator 2

2

4

High-throughput

0.628

High

1403269

ANM1
Protein arginine N-methyltransferase 1

2

10

Small-scale

0.624

High

134839

SAP18
Histone deacetylase complex subunit SAP18

1

2

High-throughput

0.618

High

401344

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

10

High-throughput

0.618

High

473003

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.618

High

485357

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

20

High-throughput

0.618

High

1088520

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

12

High-throughput

0.618

High

1132915

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

12

High-throughput

0.618

High

1368574

KAT6A
Histone acetyltransferase KAT6A

1

12

High-throughput

0.618

High

1403275

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

4

High-throughput

0.618

High

1403289

RC3H2
Roquin-2

1

11

High-throughput

0.618

High

1403292

LATS2
Serine/threonine-protein kinase LATS2

1

9

High-throughput

0.618

High

1403297

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.618

High

247413

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

2

2

High-throughput

0.611

High

1118136

DX39B
Spliceosome RNA helicase DDX39B

2

14

High-throughput

0.611

High

1316701

ABI1
Abl interactor 1

2

2

High-throughput

0.606

High

286041

SF3B1
Splicing factor 3B subunit 1

1

0

Small-scale

0.586

High

260343

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

414466

P53
Cellular tumor antigen p53

2

5

High-throughput

0.584

High

589483

RFA2
Replication protein A 32 kDa subunit

2

5

High-throughput

0.584

High

696293

RFA1
Replication protein A 70 kDa DNA-binding subunit

2

4

High-throughput

0.584

High

768967

RFA3
Replication protein A 14 kDa subunit

2

4

High-throughput

0.584

High

1403290

ANLN
Anillin

2

7

High-throughput

0.584

High

1403280

TSYL2
Testis-specific Y-encoded-like protein 2

2

0

High-throughput

0.580

High

1066755

NCBP1
Nuclear cap-binding protein subunit 1

1

4

High-throughput

0.575

High

1099211

SRSF5
Serine/arginine-rich splicing factor 5

1

20

High-throughput

0.575

High

1099490

SRSF6
Serine/arginine-rich splicing factor 6

1

20

High-throughput

0.575

High

1403287

LN28A
Protein lin-28 homolog A

1

20

High-throughput

0.575

High

1324670

MUC20
Mucin-20

2

2

High-throughput

0.574

High

1095765

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

1

High-throughput

0.573

High

157759

CTRO
Citron Rho-interacting kinase

1

16

High-throughput

0.553

High

272735

BRE1B
E3 ubiquitin-protein ligase BRE1B

1

7

High-throughput

0.536

High

542173

TOP1
DNA topoisomerase 1

1

1

High-throughput

0.536

High

788754

SRP14
Signal recognition particle 14 kDa protein

1

1

High-throughput

0.536

High

872661

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.536

High

971914

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.536

High

990640

1433Z
14-3-3 protein zeta/delta

1

13

High-throughput

0.536

High

1065382

SSRP1
FACT complex subunit SSRP1

1

4

High-throughput

0.536

High

1111213

SNW1
SNW domain-containing protein 1

1

4

High-throughput

0.536

High

1136483

FL2D
Pre-mRNA-splicing regulator WTAP

1

3

High-throughput

0.536

High

1287873

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

3

High-throughput

0.536

High

1403284

SENP3
Sentrin-specific protease 3

1

2

High-throughput

0.536

High

1403300

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

High-throughput

0.536

High

1135055

CUL7
Cullin-7

2

8

High-throughput

0.533

High

1339450

TOIP2
Torsin-1A-interacting protein 2

2

0

High-throughput

0.528

High

1403270

LZTS2
Leucine zipper putative tumor suppressor 2

1

9

High-throughput

0.523

High

1068291

AHNK
Neuroblast differentiation-associated protein AHNAK

1

4

High-throughput

0.515

High

257064

F262
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2

1

0

High-throughput

0.513

High

1371624

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

5

High-throughput

0.501

High

1384112

ARRD3
Arrestin domain-containing protein 3

1

5

High-throughput

0.489

High

1403304

KLH20
Kelch-like protein 20

1

1

High-throughput

0.489

High

1403307

WIF1
Wnt inhibitory factor 1

1

1

High-throughput

0.489

High

129355

MEN1
Menin

1

4

High-throughput

0.479

High

188346

HDAC3
Histone deacetylase 3

1

6

Small-scale

0.479

High

188972

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

223272

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.479

High

242674

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

248054

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

285427

EED
Polycomb protein EED

1

12

High-throughput

0.479

High

319994

UFL1
E3 UFM1-protein ligase 1

1

3

High-throughput

0.479

High

346222

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

20

High-throughput

0.479

High

352523

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.479

High

406538

MYCN
N-myc proto-oncogene protein

1

15

High-throughput

0.479

High

613150

EGR1
Early growth response protein 1

1

3

High-throughput

0.479

High

778095

VGFR2
Vascular endothelial growth factor receptor 2

1

3

High-throughput

0.479

High

786803

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

7

High-throughput

0.479

High

831283

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

854913

RECQ1
ATP-dependent DNA helicase Q1

1

7

High-throughput

0.479

High

879383

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

6

High-throughput

0.479

High

905060

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

962411

RHOA
Transforming protein RhoA

1

3

High-throughput

0.479

High

965176

WDR5
WD repeat-containing protein 5

1

6

High-throughput

0.479

High

966783

1433G
14-3-3 protein gamma

1

13

High-throughput

0.479

High

980187

H4
Histone H4

1

4

High-throughput

0.479

High

988636

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.479

High

1024787

VIGLN
Vigilin

1

20

High-throughput

0.479

High

1040899

MECOM
Histone-lysine N-methyltransferase MECOM

1

2

High-throughput

0.479

High

1045677

TF65
Transcription factor p65

1

2

High-throughput

0.479

High

1067627

EP300
Histone acetyltransferase p300

1

4

High-throughput

0.479

High

1107124

BIRC3
Baculoviral IAP repeat-containing protein 3

1

3

High-throughput

0.479

High

1128093

DHX8
ATP-dependent RNA helicase DHX8

1

6

High-throughput

0.479

High

1130157

SMC1A
Structural maintenance of chromosomes protein 1A

1

3

High-throughput

0.479

High

1137965

TNIP1
TNFAIP3-interacting protein 1

1

13

High-throughput

0.479

High

1140732

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1161609

IF16
Gamma-interferon-inducible protein 16

1

5

High-throughput

0.479

High

1215780

RC3H1
Roquin-1

1

9

High-throughput

0.479

High

1228461

FTM
Protein fantom

1

8

High-throughput

0.479

High

1280059

FGD2
FYVE, RhoGEF and PH domain-containing protein 2

1

8

High-throughput

0.479

High

1311840

DHX40
Probable ATP-dependent RNA helicase DHX40

1

5

High-throughput

0.479

High

1313363

SMC5
Structural maintenance of chromosomes protein 5

1

9

High-throughput

0.479

High

1314377

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

1334803

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

1338328

FBX22
F-box only protein 22

1

2

High-throughput

0.479

High

1338916

NUP43
Nucleoporin Nup43

1

9

High-throughput

0.479

High

1339668

TNIP2
TNFAIP3-interacting protein 2

1

3

High-throughput

0.479

High

1352703

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

3

High-throughput

0.479

High

1382823

FUBP1
Far upstream element-binding protein 1

1

20

High-throughput

0.479

High

1387511

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

9

High-throughput

0.479

High

1397331

CI072
Guanine nucleotide exchange factor C9orf72

1

4

High-throughput

0.479

High

1403268

TBX5
T-box transcription factor TBX5

1

3

High-throughput

0.479

High

1403274

DDX23
Probable ATP-dependent RNA helicase DDX23

1

7

High-throughput

0.479

High

1403276

FACD2
Fanconi anemia group D2 protein

1

3

High-throughput

0.479

High

1403278

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

1403291

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

4

High-throughput

0.479

High

1403294

RAD18
E3 ubiquitin-protein ligase RAD18

1

2

High-throughput

0.479

High

1403302

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

1403303

SMC3
Structural maintenance of chromosomes protein 3

1

3

High-throughput

0.479

High

1403306

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.479

High

460865

CATB
Cathepsin B

1

1

High-throughput

0.470

High

459326

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

647631

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

Small-scale

0.458

High

800064

COIL
Coilin

1

0

High-throughput

0.458

High

941959

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

1156825

E2F4
Transcription factor E2F4

1

0

High-throughput

0.458

High

1177623

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.458

High

1279221

WAPL
Wings apart-like protein homolog

1

0

High-throughput

0.458

High

1325377

STAG2
Cohesin subunit SA-2

1

0

High-throughput

0.458

High

463207

YES
Tyrosine-protein kinase Yes

1

3

High-throughput

0.457

High

191768

MAGB2
Melanoma-associated antigen B2

1

4

High-throughput

0.445

High

321643

PRP6
Pre-mRNA-processing factor 6

1

10

High-throughput

0.445

High

480281

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.445

High

1198641

NCBP3
Nuclear cap-binding protein subunit 3

1

4

High-throughput

0.445

High

1199665

KLH22
Kelch-like protein 22

1

3

High-throughput

0.445

High

1327328

ZN276
Zinc finger protein 276

1

3

High-throughput

0.445

High

1346896

SNIP1
Smad nuclear-interacting protein 1

1

1

High-throughput

0.445

High

1403272

ZN692
Zinc finger protein 692

1

5

High-throughput

0.445

High

1403288

EAF6
Chromatin modification-related protein MEAF6

1

1

High-throughput

0.445

High

1403298

DDX41
Probable ATP-dependent RNA helicase DDX41

1

6

High-throughput

0.445

High

1403305

LC7L2
Putative RNA-binding protein Luc7-like 2

1

6

High-throughput

0.445

High

1124694

SRC8
Src substrate cortactin

1

3

High-throughput

0.439

High

1146111

K1H1
Keratin, type I cuticular Ha1

1

1

High-throughput

0.439

High

272403

OBSL1
Obscurin-like protein 1

1

5

High-throughput

0.437

High

294214

CD123
Translation initiation factor eIF2 assembly protein

1

2

High-throughput

0.437

High

412478

NTRK1
High affinity nerve growth factor receptor

1

8

High-throughput

0.437

High

581248

RAC2
Ras-related C3 botulinum toxin substrate 2

1

3

High-throughput

0.437

High

650370

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.437

High

720308

UFO
Tyrosine-protein kinase receptor UFO

1

6

High-throughput

0.437

High

1023027

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

1

8

High-throughput

0.437

High

1049699

1433F
14-3-3 protein eta

1

13

High-throughput

0.437

High

1088207

MERTK
Tyrosine-protein kinase Mer

1

7

High-throughput

0.437

High

1253733

RHG36
Rho GTPase-activating protein 36

1

2

High-throughput

0.437

High

1255183

TRI67
Tripartite motif-containing protein 67

1

16

High-throughput

0.437

High

1286881

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

1357412

DEP1B
DEP domain-containing protein 1B

1

3

High-throughput

0.437

High

1393615

DDRGK
DDRGK domain-containing protein 1

1

3

High-throughput

0.437

High

1403277

ACE2
Angiotensin-converting enzyme 2

1

2

High-throughput

0.437

High

1403283

RHOJ
Rho-related GTP-binding protein RhoJ

1

4

High-throughput

0.437

High

1403285

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.437

High

1403293

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

1403299

VAV3
Guanine nucleotide exchange factor VAV3

1

10

High-throughput

0.437

High

1403301

HECD1
E3 ubiquitin-protein ligase HECTD1

1

10

High-throughput

0.437

High

208347

RRP8
Ribosomal RNA-processing protein 8

1

0

High-throughput

0.426

High

290689

SURF6
Surfeit locus protein 6

1

0

High-throughput

0.426

High

428927

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.426

High

584136

FOSL2
Fos-related antigen 2

1

0

High-throughput

0.426

High

911352

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.426

High

1244325

PSRC1
Proline/serine-rich coiled-coil protein 1

1

0

High-throughput

0.426

High

1403273

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.426

High

887151

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

1023864

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.407

High

1210963

CE170
Centrosomal protein of 170 kDa

1

10

High-throughput

0.407

High

1396565

C170L
Cep170-like protein

1

3

High-throughput

0.407

High

1403281

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

14

High-throughput

0.407

High

829918

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.328

High

1403282

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

2

0

High-throughput

0.305

High

1403279

CEP44
Centrosomal protein of 44 kDa

1

0

High-throughput

0.299

High

1127466

FGFP1
Fibroblast growth factor-binding protein 1

1

0

High-throughput

0.279

Low

1403271

THTPA
Thiamine-triphosphatase

1

0

High-throughput

0.279

Low

488845

FURIN
Furin

1

0

High-throughput

0.249

Low

693062

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.249

Low

1060721

SOS2
Son of sevenless homolog 2

1

0

High-throughput

0.249

Low

1235254

ANO7
Anoctamin-7

1

0

Small-scale

0.249

Low

1322432

SPICE
Spindle and centriole-associated protein 1

1

0

High-throughput

0.249

Low

1332884

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low

1360921

CLC4D
C-type lectin domain family 4 member D

1

0

High-throughput

0.249

Low

1403286

GHC1
Mitochondrial glutamate carrier 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025