Interactor 1: MICB (Q29980)
MHC class I polypeptide-related sequence B (MIC-B)
Gene: MICB

Interactor 2: MICA (Q29983)
MHC class I polypeptide-related sequence A (MIC-A)
Gene: MICA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains C1-set~C1-set, C1-set~MHC_I, MHC_I~MHC_I
Common GO terms GO:0001916 - positive regulation of T cell mediated cytotoxicity
GO:0002476 - antigen processing and presentation of endogenous peptide antigen via MHC class Ib
GO:0002486 - antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
GO:0005102 - signaling receptor binding
GO:0005615 - extracellular space
and 9 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 383
Hs

1 383
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024