Protein: HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)

Gene: HM20B, HMG20B
Organism: Homo sapiens
Interactions: 87
UniProt ID: Q9P0W2

Gene Ontology (top 5):
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005694 - chromosome
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1445897

HM20A
High mobility group protein 20A

7

20

Small-scale

0.969

High

1110133

HDAC1
Histone deacetylase 1

10

20

Small-scale

0.758

High

1368164

HDAC2
Histone deacetylase 2

8

20

Small-scale

0.754

High

246998

KDM1A
Lysine-specific histone demethylase 1A

9

20

Small-scale

0.753

High

1384460

PF21A
PHD finger protein 21A

6

20

Small-scale

0.735

High

1454092

RCOR1
REST corepressor 1

5

20

Small-scale

0.718

High

904398

BRCA2
Breast cancer type 2 susceptibility protein

4

2

Small-scale

0.711

High

350160

SNAI1
Zinc finger protein SNAI1

3

6

High-throughput

0.667

High

1454090

RCOR3
REST corepressor 3

3

20

High-throughput

0.667

High

384572

CRYAA
Alpha-crystallin A chain

2

4

High-throughput

0.621

High

776138

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.618

High

776258

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.618

High

1228732

C102B
Coiled-coil domain-containing protein 102B

3

4

High-throughput

0.616

High

1054803

SUH
Recombining binding protein suppressor of hairless

2

2

High-throughput

0.611

High

1130670

GSE1
Genetic suppressor element 1

3

3

High-throughput

0.609

High

1315926

RCOR2
REST corepressor 2

3

20

High-throughput

0.609

High

297872

PIAS2
E3 SUMO-protein ligase PIAS2

2

6

High-throughput

0.606

High

965589

NTF2
Nuclear transport factor 2

2

5

High-throughput

0.606

High

1396271

ASPP1
Apoptosis-stimulating of p53 protein 1

2

14

High-throughput

0.606

High

300849

KRT38
Keratin, type I cuticular Ha8

2

13

High-throughput

0.594

High

143299

NFIB
Nuclear factor 1 B-type

2

20

High-throughput

0.584

High

1402329

RANB9
Ran-binding protein 9

2

17

Small-scale

0.584

High

299850

SNPC5
snRNA-activating protein complex subunit 5

2

0

High-throughput

0.580

High

1395360

CC136
Coiled-coil domain-containing protein 136

2

10

High-throughput

0.578

High

331605

KIF4A
Chromosome-associated kinesin KIF4A

1

3

Small-scale

0.573

High

618124

K1C15
Keratin, type I cytoskeletal 15

1

9

High-throughput

0.573

High

1322150

SYCE1
Synaptonemal complex central element protein 1

1

1

High-throughput

0.573

High

1454091

TFP11
Tuftelin-interacting protein 11

1

2

High-throughput

0.573

High

397106

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

716235

ERP29
Endoplasmic reticulum resident protein 29

2

4

High-throughput

0.553

High

1330104

USBP1
Harmonin-binding protein USHBP1

2

7

High-throughput

0.553

High

334321

TACC2
Transforming acidic coiled-coil-containing protein 2

1

7

High-throughput

0.541

High

576582

HNRPL
Heterogeneous nuclear ribonucleoprotein L

1

12

High-throughput

0.541

High

1154605

CC85B
Coiled-coil domain-containing protein 85B

1

1

High-throughput

0.541

High

445275

S10A6
Protein S100-A6

1

4

High-throughput

0.536

High

1123154

FHL2
Four and a half LIM domains protein 2

1

5

High-throughput

0.536

High

1411500

OVOL2
Transcription factor Ovo-like 2

1

4

High-throughput

0.536

High

186594

TRI18
E3 ubiquitin-protein ligase Midline-1

1

15

Small-scale

0.528

High

844041

HD
Huntingtin

1

5

High-throughput

0.515

High

1279778

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

2

High-throughput

0.515

High

1289901

Q86V38
Atrophin 1

1

20

High-throughput

0.515

High

1369713

KLK6
Kallikrein-6

1

5

High-throughput

0.515

High

608371

EGLN
Endoglin

1

0

High-throughput

0.513

High

423362

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

1454094

FBX7
F-box only protein 7

1

3

High-throughput

0.501

High

475032

VIME
Vimentin

1

6

High-throughput

0.494

High

1241051

L2GL2
LLGL scribble cell polarity complex component 2

1

5

High-throughput

0.489

High

282791

E2F6
Transcription factor E2F6

1

5

Small-scale

0.481

High

1407370

NKX31
Homeobox protein Nkx-3.1

1

20

Small-scale

0.481

High

1413296

WAC
WW domain-containing adapter protein with coiled-coil

1

8

High-throughput

0.481

High

173483

XPO1
Exportin-1

1

16

High-throughput

0.479

High

181571

TBXT
T-box transcription factor T

1

11

High-throughput

0.479

High

226613

TLX2
T-cell leukemia homeobox protein 2

1

20

High-throughput

0.479

High

289184

PRDM1
PR domain zinc finger protein 1

1

5

High-throughput

0.479

High

474338

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

520412

ANDR
Androgen receptor

1

20

High-throughput

0.479

High

607172

CEBPB
CCAAT/enhancer-binding protein beta

1

17

High-throughput

0.479

High

662288

PAX7
Paired box protein Pax-7

1

20

High-throughput

0.479

High

662510

GATA2
Endothelial transcription factor GATA-2

1

19

High-throughput

0.479

High

685367

PAX6
Paired box protein Pax-6

1

20

High-throughput

0.479

High

775924

HNF1B
Hepatocyte nuclear factor 1-beta

1

20

High-throughput

0.479

High

834074

HNF4A
Hepatocyte nuclear factor 4-alpha

1

16

High-throughput

0.479

High

887282

CEBPA
CCAAT/enhancer-binding protein alpha

1

16

High-throughput

0.479

High

938512

PAX9
Paired box protein Pax-9

1

17

High-throughput

0.479

High

942472

GSC
Homeobox protein goosecoid

1

20

High-throughput

0.479

High

980458

H4
Histone H4

1

14

High-throughput

0.479

High

1040085

PAX2
Paired box protein Pax-2

1

20

High-throughput

0.479

High

1056657

PAX8
Paired box protein Pax-8

1

20

High-throughput

0.479

High

1088067

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1148665

SF3A2
Splicing factor 3A subunit 2

1

14

Small-scale

0.479

High

1160899

TBR1
T-box brain protein 1

1

11

High-throughput

0.479

High

1351179

SP7
Transcription factor Sp7

1

8

High-throughput

0.479

High

1405447

FEV
Protein FEV

1

15

High-throughput

0.479

High

1413352

MTA3
Metastasis-associated protein MTA3

1

20

High-throughput

0.479

High

1420508

FOXQ1
Forkhead box protein Q1

1

20

High-throughput

0.479

High

1445866

GCM1
Chorion-specific transcription factor GCMa

1

2

High-throughput

0.479

High

1454093

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

20

High-throughput

0.479

High

1292943

Q86WV8
TSC complex subunit 1

1

1

High-throughput

0.470

High

1093985

TRAF1
TNF receptor-associated factor 1

1

5

High-throughput

0.464

High

402693

ALDOA
Fructose-bisphosphate aldolase A

1

0

High-throughput

0.458

High

1326125

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1453268

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

1396839

SNX27
Sorting nexin-27

1

3

High-throughput

0.437

High

1227603

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.407

High

1353335

DOK4
Docking protein 4

1

1

High-throughput

0.407

High

1451259

CN119
Uncharacterized protein C14orf119

2

0

High-throughput

0.316

High

1281397

LHPL4
LHFPL tetraspan subfamily member 4 protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025