HitPredict

Interactor 1: TBC25 (Q3MII6)
TBC1 domain family member 25
Gene: TBC1D25

Interactor 2: MLP3C (Q9BXW4)
Microtubule-associated proteins 1A/1B light chain 3C (Autophagy-related protein LC3 C) (Autophagy-related ubiquitin-like modifier LC3 C) (MAP1 light chain 3-like protein 3) (MAP1A/MAP1B light chain 3 C) (MAP1A/MAP1B LC3 C) (Microtubule-associated protein 1 light chain 3 gamma)
Gene: MAP1LC3C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005776 - autophagosome GO:0031410 - cytoplasmic vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 688 Hs			1 147
+	Hs
		306201 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891174 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1109691 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1109689 TBC25_HUMAN (1-688): 0: 735: 100.00		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1109690 TBC25_HUMAN (1-688): 0: 735: 100.00		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1253202 TBC15_HUMAN (137-475): 2.54e-86: 287: 31.11		MLP3C_HUMAN (1-147): 4.64e-72: 214: 100.00
+	Hs
		1315254 TB10A_HUMAN (127-614): 4.12e-95: 305: 16.53		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1315253 TB10A_HUMAN (127-614): 4.12e-95: 305: 16.53		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		306240 TBC15_HUMAN (137-475): 2.54e-86: 287: 31.11		GBRAP_HUMAN (13-127): 3.44e-54: 168: 38.26
+	Hs
		891232 TBC15_HUMAN (137-475): 2.54e-86: 287: 31.11		GBRL2_HUMAN (13-126): 1.65e-54: 168: 42.98
+	Hs
		1253204 TBC15_HUMAN (137-475): 2.54e-86: 287: 31.11		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1253208 TBC15_HUMAN (137-475): 2.54e-86: 287: 31.11		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Dm
		1364630 Q9VPL5_DROME (112-475): 1.79e-78: 266: 27.08		Q9VEG5_DROME (13-126): 2.29e-51: 160: 38.60
+	Hs
		1198510 TBCD1_HUMAN (78-609): 9.38e-74: 260: 16.42		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1198509 TBCD1_HUMAN (78-609): 9.38e-74: 260: 16.42		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1117431 TB10B_HUMAN (114-617): 1.78e-72: 252: 15.89		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1117430 TB10B_HUMAN (114-617): 1.78e-72: 252: 15.89		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47
+	Hs
		1330629 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3A_HUMAN (7-126): 2.49e-53: 165: 59.17
+	Hs
		1326155 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		MLP3B_HUMAN (7-127): 8.15e-53: 164: 54.55
+	Hs
		1328034 TBC17_HUMAN (194-550): 1.7e-72: 249: 31.22		GBRL1_HUMAN (13-126): 4.75e-52: 162: 39.47