HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: RNPS1 (Q15287)
RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2)
Gene: RNPS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.858

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 305
+	Hs
		988124 TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25		RNPS1_HUMAN (1-234): 1.24e-34: 129: 100.00
+	Hs
		988235 TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		550522 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		PPIE_HUMAN (159-297): 4.43e-33: 125: 17.73
+	Hs
		550269 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Hs
		1102145 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Hs
		550546 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		RBM8A_HUMAN (95-239): 7.05e-31: 115: 21.38
+	Hs
		550190 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		911574 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		NCBP2_HUMAN (128-271): 1.09e-30: 114: 18.06
+	Hs
		1101941 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		PABP4_HUMAN (153-248): 3.7e-19: 89.6: 27.08
+	Hs
		506130 TRA2A_HUMAN (1-253): 2.2e-47: 161: 100.00		PAB4L_HUMAN (161-242): 1.23e-18: 86.9: 30.49
+	Hs
		550217 TRA2B_HUMAN (1-257): 9.05e-43: 149: 55.25		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Hs
		550311 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		PAP1L_HUMAN (65-252): 1.73e-22: 99.2: 14.21
+	Hs
		550097 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Hs
		550262 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		PABP1_HUMAN (65-252): 1.03e-21: 97.3: 16.32
+	Hs
		506129 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		PAB4L_HUMAN (161-242): 1.23e-18: 86.9: 30.49
+	Hs
		550237 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		TIAR_HUMAN (155-250): 1.51e-18: 86.9: 27.08
+	Hs
		550137 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		TIA1_HUMAN (156-251): 2.6e-18: 86.1: 27.08
+	Hs
		1102095 PABP4_HUMAN (1-267): 1.76e-37: 141: 14.49		PABP3_HUMAN (153-248): 3.53e-17: 83.8: 26.04
+	Hs
		550464 PABP1_HUMAN (1-267): 2.44e-37: 141: 14.13		PABP3_HUMAN (153-248): 3.53e-17: 83.8: 26.04