HitPredict

Interactor 1: PABP1 (P11940)
Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Gene: PABPC1

Interactor 2: TRA2B (P62995)
Transformer-2 protein homolog beta (TRA-2 beta) (TRA2-beta) (hTRA2-beta) (Splicing factor, arginine/serine-rich 10) (Transformer-2 protein homolog B)
Gene: TRA2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 288
+	Hs
		550269 PABP1_HUMAN (1-636): 0: 571: 100.00		TRA2A_HUMAN (1-237): 9.37e-36: 131: 62.06
+	Hs
		550522 PABP1_HUMAN (1-636): 0: 571: 100.00		PPIE_HUMAN (118-201): 7.9e-27: 107: 36.91
+	Hs
		550250 PABP1_HUMAN (1-636): 0: 571: 100.00		ELAV2_HUMAN (52-244): 5.96e-24: 101: 20.00
+	Hs
		550311 PABP1_HUMAN (1-636): 0: 571: 100.00		PAP1L_HUMAN (53-281): 9.51e-23: 99.5: 15.97
+	Hs
		550262 PABP1_HUMAN (1-636): 0: 571: 100.00		PABP4_HUMAN (109-246): 1.66e-22: 99.2: 21.28
+	Hs
		550097 PABP1_HUMAN (1-636): 0: 571: 100.00		PABP1_HUMAN (109-246): 3.02e-22: 98.4: 21.99
+	Hs
		550464 PABP1_HUMAN (1-636): 0: 571: 100.00		PABP3_HUMAN (109-246): 4.58e-20: 91.8: 19.86
+	Hs
		550237 PABP1_HUMAN (1-636): 0: 571: 100.00		TIAR_HUMAN (73-272): 5.49e-20: 90.6: 14.00
+	Hs
		550285 PABP1_HUMAN (1-636): 0: 571: 100.00		RBM39_HUMAN (15-248): 1.55e-18: 87.2: 21.83
+	Hs
		1101941 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		TRA2A_HUMAN (1-237): 9.37e-36: 131: 62.06
+	Mm
		710979 PABP1_MOUSE (1-636): 0: 570: 99.69		TIA1_MOUSE (113-284): 2.21e-18: 86: 15.53
+	Hs
		550137 PABP1_HUMAN (1-636): 0: 571: 100.00		TIA1_HUMAN (113-248): 7.98e-18: 84.5: 18.42
+	Hs
		1197178 PABP3_HUMAN (1-636): 0: 537: 91.68		PAP1L_HUMAN (53-281): 9.51e-23: 99.5: 15.97
+	Hs
		1102095 PABP3_HUMAN (1-636): 0: 537: 91.68		PABP4_HUMAN (109-246): 1.66e-22: 99.2: 21.28
+	Hs
		550278 PABP1_HUMAN (1-636): 0: 571: 100.00		HNRPD_HUMAN (106-178): 6.08e-11: 64: 26.03
+	Hs
		1090216 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		ELAV2_HUMAN (52-244): 5.96e-24: 101: 20.00
+	Hs
		1101955 PABP4_HUMAN (1-635): 4.43e-180: 527: 72.87		RBM39_HUMAN (15-248): 1.55e-18: 87.2: 21.83