HitPredict

Interactor 1: I7GPR1 (I7GPR1)
TRAF3 interacting protein 2
Gene: Traf3ip2

Interactor 2: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23042150
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 555 Mm			1 530
+	Mm
		936263 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF6_MOUSE (1-530): 1.94e-141: 420: 100.00
+	Mm
		936253 Q8C0E5_MOUSE (1-555): 0: 1014: 98.92		TRAF6_MOUSE (1-530): 1.94e-141: 420: 100.00
+	Hs
		212277 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF6_HUMAN (1-530): 1.18e-143: 425: 87.93
+	Mm
		761830 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF2_MOUSE (38-508): 8.88e-104: 322: 25.75
+	Mm
		1141427 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF3_MOUSE (14-510): 9.77e-92: 293: 21.64
+	Mm
		1142553 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF4_MOUSE (54-515): 3.05e-92: 291: 25.68
+	Mm
		111225 I7GPR1_MOUSE (1-555): 0: 1019: 100.00		TRAF5_MOUSE (43-508): 3.04e-84: 273: 24.35
+	Mm
		936209 CIKS_MOUSE (1-555): 0: 1015: 99.10		TRAF5_MOUSE (43-508): 3.04e-84: 273: 24.35
+	Hs
		212248 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF2_HUMAN (38-508): 2.54e-103: 321: 25.55
+	Hs
		212251 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF3_HUMAN (14-510): 1.85e-90: 290: 20.94
+	Hs
		129517 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF5_HUMAN (43-508): 2.7e-84: 273: 23.61
+	Hs
		212249 CIKS_HUMAN (1-555): 0: 917: 78.50		TRAF1_HUMAN (42-511): 3.5e-66: 221: 19.30