HitPredict

Interactor 1: PP1R7 (Q3UM45)
Protein phosphatase 1 regulatory subunit 7 (Protein phosphatase 1 regulatory subunit 22)
Gene: Ppp1r7

Interactor 2: SHAN3 (Q4ACU6)
SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)
Gene: Shank3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	27507650, 28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 361 Mm			1 1730
+	Mm
		1115982 LRRC7_MOUSE (3-315): 8.41e-44: 163: 19.69		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Mm
		471546 LRC4B_MOUSE (165-361): 9.56e-29: 119: 22.12		SHAN3_MOUSE (1-1730): 0: 626: 100.00
+	Hs
		862032 FLII_HUMAN (7-198): 1.89e-22: 101: 13.31		DAPK1_HUMAN (17-450): 1.03e-87: 318: 15.97
+	Hs
		1301444 ERBIN_HUMAN (2-295): 9.65e-34: 134: 19.14		Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21
+	Hs
		883609 ERBIN_HUMAN (2-295): 9.65e-34: 134: 19.14		RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21
+	Hs
		1023235 FLII_HUMAN (7-198): 1.89e-22: 101: 13.31		Q9H4D1_HUMAN (1-279): 6.7e-66: 242: 18.21
+	Hs
		883498 FLII_HUMAN (7-198): 1.89e-22: 101: 13.31		RIPK4_HUMAN (1-279): 5.68e-65: 240: 18.21
+	Hs
		1205973 LRC49_HUMAN (73-260): 3.73e-33: 131: 33.67		MIB1_HUMAN (187-625): 7.14e-50: 195: 10.66
+	Hs
		1050092 SCRIB_HUMAN (9-228): 3.78e-30: 123: 16.40		ANR50_HUMAN (197-1044): 5.47e-49: 194: 10.39
+	Hs
		1315169 LGR4_HUMAN (3-326): 1.5e-37: 145: 19.31		KDIS_HUMAN (258-430): 1.28e-21: 105: 16.19
+	Hs
		1298929 LRRC7_HUMAN (3-315): 1.18e-42: 160: 20.31		SHAN1_HUMAN (491-1637): 5.93e-12: 73.4: 14.37