HitPredict

Interactor 1: LCE2B (O14633)
Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B)
Gene: LCE2B

Interactor 2: KRA59 (P26371)
Keratin-associated protein 5-9 (Keratin, cuticle, ultrahigh sulfur 1) (Keratin, ultra high-sulfur matrix protein A) (Keratin-associated protein 5.9) (UHS keratin A) (UHS KerA) (Ultrahigh sulfur keratin-associated protein 5.9)
Gene: KRTAP5-9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008544 - epidermis development
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 110 Hs			1 169
+	Hs
		150453 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA13_HUMAN (8-166): 8.07e-21: 85.5: 26.25
+	Hs
		150422 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR109_HUMAN (39-168): 9.93e-17: 77.1: 26.14
+	Hs
		150424 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA11_HUMAN (31-167): 3.12e-15: 71.3: 30.44
+	Hs
		150461 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR412_HUMAN (35-166): 1.04e-14: 70.1: 33.33
+	Hs
		150474 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA15_HUMAN (3-165): 1.02e-14: 69.7: 21.30
+	Hs
		150421 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR108_HUMAN (26-165): 4.36e-14: 69.4: 28.87
+	Hs
		150466 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA92_HUMAN (47-166): 3.82e-14: 68.2: 34.71
+	Hs
		150418 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR101_HUMAN (7-162): 7.55e-13: 66.3: 28.30
+	Hs
		150465 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA93_HUMAN (63-166): 1.18e-12: 64: 29.81
+	Hs
		150467 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR411_HUMAN (1-131): 4.08e-12: 63.2: 25.19
+	Hs
		150468 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA45_HUMAN (7-160): 5.89e-12: 62.4: 26.04
+	Hs
		150469 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA44_HUMAN (1-127): 4.34e-12: 62.4: 29.13
+	Hs
		150419 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR106_HUMAN (26-165): 1.15e-10: 60.5: 26.99
+	Hs
		150464 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA98_HUMAN (52-167): 1.94e-11: 60.5: 35.04
+	Hs
		150416 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR122_HUMAN (54-166): 4.13e-10: 57: 29.20
+	Hs
		150420 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR107_HUMAN (26-165): 1.87e-09: 57: 25.30
+	Hs
		150415 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR121_HUMAN (38-127): 2.72e-10: 56.2: 23.08
+	Hs
		150470 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KRA42_HUMAN (11-107): 9.97e-10: 55.5: 24.24
+	Hs
		150417 LCE2B_HUMAN (1-110): 8.37e-46: 145: 100.00		KR123_HUMAN (6-98): 8.5e-10: 54.7: 23.16