HitPredict

Interactor 1: SCE1 (Q42551)
SUMO-conjugating enzyme SCE1 (EC 2.3.2.-) (Protein EMBRYO DEFECTIVE 1637) (Protein hus5 homolog) (SUMO-conjugating enzyme 1) (AtSCE1)
Gene: SCE1

Interactor 2: SAE2 (Q9SJT1)
SUMO-activating enzyme subunit 2 (EC 2.3.2.-) (Protein EMBRYO DEFECTIVE 2764) (Ubiquitin-like 1-activating enzyme E1B)
Gene: SAE2

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.767

Property	Details
Experiments	20855607, 24434138
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ThiF~UQ_con, UAE_UbL~UQ_con
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0009793 - embryo development ending in seed dormancy GO:0016925 - protein sumoylation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 160 At			1 700
+	Hs
		1282360 UB2E3_HUMAN (4-157): 1.03e-67: 205: 31.82		SAE2_HUMAN (3-530): 6.31e-173: 510: 41.87
+	Hs
		930429 UBC9_HUMAN (3-157): 5.24e-68: 205: 65.81		SAE2_HUMAN (3-530): 6.31e-173: 510: 41.87
+	Dm
		1181395 Q7KNM2_DROME (3-158): 8.63e-67: 201: 62.18		Q7KUA4_DROME (3-530): 3.61e-163: 488: 37.74
+	Hs
		919796 UB2D2_HUMAN (5-158): 1.09e-73: 218: 31.82		UBA3_HUMAN (282-528): 6.19e-50: 183: 21.24
+	Hs
		607190 UB2D4_HUMAN (5-158): 9.82e-75: 221: 33.77		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		607026 UB2D1_HUMAN (5-158): 4.65e-74: 220: 33.77		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		607050 UB2D2_HUMAN (5-158): 1.09e-73: 218: 31.82		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		607039 UB2D3_HUMAN (5-158): 1.64e-72: 215: 31.82		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Sc
		549788 UBC4_YEAST (1-157): 3.41e-72: 215: 33.12		UBA1_YEAST (3-526): 9.1e-31: 131: 13.42
+	Hs
		607136 UB2E2_HUMAN (4-157): 6.42e-68: 206: 31.82		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		607055 UBC9_HUMAN (3-157): 5.24e-68: 205: 65.81		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		607129 UB2E3_HUMAN (4-157): 1.03e-67: 205: 31.82		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		48104 UB2D1_HUMAN (5-158): 4.65e-74: 220: 33.77		UBA6_HUMAN (3-528): 2.12e-27: 121: 13.38
+	Hs
		48107 UB2D2_HUMAN (5-158): 1.09e-73: 218: 31.82		UBA6_HUMAN (3-528): 2.12e-27: 121: 13.38
+	Hs
		607028 UB2E1_HUMAN (4-157): 6.73e-66: 200: 30.52		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Sp
		293848 UBC4_SCHPO (5-157): 3.73e-72: 215: 33.99		UBA1_SCHPO (3-539): 3.18e-28: 123: 12.59
+	Hs
		607023 UBE2A_HUMAN (3-156): 2.29e-65: 198: 40.91		UBA1_HUMAN (3-530): 2.17e-33: 139: 14.49
+	Hs
		48106 UB2D3_HUMAN (5-158): 1.64e-72: 215: 31.82		UBA6_HUMAN (3-528): 2.12e-27: 121: 13.38
+	Sc
		608711 UBC9_YEAST (3-156): 1.37e-64: 196: 59.74		UBA1_YEAST (3-526): 9.1e-31: 131: 13.42
+	Hs
		782203 UB2E1_HUMAN (4-157): 6.73e-66: 200: 30.52		UBA7_HUMAN (3-149): 1.97e-28: 124: 23.13