Interactor 1: EXOS2 (Q13868)
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)
Gene: EXOSC2
Interactor 2: EXOS3 (Q9NQT5)
Exosome complex component RRP40 (Exosome component 3) (Ribosomal RNA-processing protein 40) (p10)
Gene: EXOSC3
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.977 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26186194, 28514442, 32188736, 33961781, 31839598, 20531389, 26496610, 24981860, 16396833, 11719186, 21255825 |
| Identification Methods | affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | KH_6~RRP40_N_mamm, KH_6~RRP40_S1, KH_6~RRP4_S1 |
| Common GO terms | GO:0000175 - 3'-5'-RNA exonuclease activity GO:0000176 - nuclear exosome (RNase complex) GO:0000177 - cytoplasmic exosome (RNase complex) GO:0000178 - exosome (RNase complex) GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and 16 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
