Interactor 1: EXOS3 (Q8IPX7)
Exosome complex component RRP40 (Ribosomal RNA-processing protein 40)
Gene: Rrp40

Interactor 2: Q9W1M9 (Q9W1M9)
Exosome complex component RRP4 (Exosome component 2) (Ribosomal RNA-processing protein 4)
Gene: Rrp4

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KH_6~RRP4_S1, KH_6~Rrp40_N, KH_6~RRP40_S1
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000177 - cytoplasmic exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000467 - exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000956 - nuclear-transcribed mRNA catabolic process
and 8 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 232
Dm

1 298
+ Hs
+ At
+ Sp
+ Sc
+ Dm
+ Hs
+ Tb

Service provided by Combinatics, Japan

Last updated: 11Aug2025