HitPredict

Interactor 1: HNRPD (Q14103)
Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0) (AU-rich element RNA-binding protein 1)
Gene: HNRNPD

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26318153
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 355 Hs			1 482
+	Hs
		1100765 HNRPD_HUMAN (1-355): 8.61e-72: 229: 100.00		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1102135 PABP4_HUMAN (88-272): 8.47e-43: 159: 19.58		G3BP2_HUMAN (1-482): 6.03e-108: 330: 100.00
+	Hs
		550520 PABP1_HUMAN (88-272): 3.12e-42: 157: 17.99		G3BP2_HUMAN (1-482): 6.03e-108: 330: 100.00
+	Hs
		1100952 MSI2H_HUMAN (78-354): 2.22e-57: 191: 35.57		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1100981 ROAA_HUMAN (30-355): 4.07e-56: 188: 53.89		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		909557 ROA3_HUMAN (64-265): 4.79e-51: 176: 37.02		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Dm
		1344374 Q9VBQ1_DROME (26-277): 2.09e-74: 243: 34.90		Q8SYC0_DROME (94-414): 4.51e-53: 184: 14.72
+	Hs
		1100748 PABP4_HUMAN (88-272): 8.47e-43: 159: 19.58		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		550261 PABP1_HUMAN (88-272): 3.12e-42: 157: 17.99		G3BP1_HUMAN (1-460): 6.21e-83: 265: 56.81
+	Hs
		1120163 HNRPD_HUMAN (1-355): 8.61e-72: 229: 100.00		SAFB1_HUMAN (141-482): 2.08e-42: 163: 16.43
+	Sc
		403606 PABP_YEAST (77-266): 1.04e-39: 149: 21.13		BRE5_YEAST (9-419): 2.99e-56: 197: 15.59
+	Dm
		1064224 SQD_DROME (78-264): 4.25e-42: 151: 42.55		Q8SYC0_DROME (94-414): 4.51e-53: 184: 14.72
+	Hs
		1120264 HNRPD_HUMAN (1-355): 8.61e-72: 229: 100.00		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Dm
		1303362 Q8IMS8_DROME (25-355): 1.63e-50: 179: 26.29		Q8IP90_DROME (199-415): 2.58e-24: 108: 12.05
+	Hs
		172159 HNRDL_HUMAN (89-355): 3.72e-57: 193: 62.63		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		1369827 ROAA_HUMAN (30-355): 4.07e-56: 188: 53.89		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Dm
		146014 SQD_DROME (78-264): 4.25e-42: 151: 42.55		O02374_DROME (199-415): 6.51e-25: 109: 12.05
+	Hs
		909641 ROA3_HUMAN (64-265): 4.79e-51: 176: 37.02		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		1102044 PABP4_HUMAN (88-272): 8.47e-43: 159: 19.58		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63
+	Hs
		550393 PABP1_HUMAN (88-272): 3.12e-42: 157: 17.99		CELF1_HUMAN (323-419): 5.01e-15: 79.2: 18.63